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Dosage Calculation: Cyclosporine

Osmosis Team
Published on Jan 8, 2024. Updated on Jan 6, 2024.

Dosage calculation for cyclosporine, a medication commonly used for rejection prophylaxis in kidney transplant patients, is crucial for patient safety. Learn how to accurately calculate and administer the appropriate dosage.


A client weighing 65 kg is prescribed cyclosporine for rejection prophylaxis in preparation for a kidney transplant. The nurse preparing to administer the medication reviews the prescription:

“Cyclosporine 5 mg/kg intravenously, infused over 3 hours.”

The nurse must first draw up the appropriate dose from a vial containing 250 mg/5 mL. Which volume (mL) should the nurse prepare to reconstitute for administration?

Round to the nearest tenth.

Use a leading zero if it applies. Do not use a trailing zero. Any rounding should be completed at the end of the calculation. The answer must be numeric only. Do not add any units of measurement.

Answer: 6.5mL

dosage calculation for cyclosporine

Learn more about cyclosporine here!