{"id":1463,"date":"2022-03-16T20:04:00","date_gmt":"2022-03-16T20:04:00","guid":{"rendered":"https:\/\/www.osmosis.org\/blog\/?p=1463"},"modified":"2026-03-20T13:51:43","modified_gmt":"2026-03-20T21:51:43","slug":"nclex-question-of-the-day-tumor-lysis-syndrome","status":"publish","type":"post","link":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome","title":{"rendered":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-center counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">In This Article<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\" >The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#B_Potassium_level_of_61_mEqL\" >B. Potassium level of 6.1 mEq\/L<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#Main_takeaway\" >Main takeaway<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#Incorrect_answer_explanations\" >Incorrect answer explanations<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#A_Phosphorus_level_of_44_mgdL\" >A. Phosphorus level of 4.4 mg\/dL<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#C_Calcium_level_of_84_mgdL\" >C. Calcium level of 8.4 mg\/dL<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#D_Uric_acid_level_of_69_mgdL\" >D. Uric acid level of 6.9 mg\/dL<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\/#References\" >References<\/a><\/li><\/ul><\/nav><\/div>\n\n<p class=\"wp-block-paragraph\"><em><strong>Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a nurse reviewing laboratory results on an oncology unit.&nbsp;<\/strong><\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The nurse is reviewing the blood work drawn for a client on the oncology unit. The nurse should recognize which laboratory result correlates with a diagnosis of tumor lysis syndrome (TLS)?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. Phosphorus level of 4.4 mg\/dL<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Potassium level of 6.1 mEq\/L<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. Calcium level of 8.4 mg\/dL<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. Uric acid level of 6.9 mg\/dL<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Scroll down for the correct answer!<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-embed-handler wp-block-embed-embed-handler wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Nurses Learn by Osmosis.org\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/kGJCkPfFypA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><a href=\"https:\/\/www.osmosis.org\/plans\" target=\"_blank\" rel=\"noreferrer noopener\"><br><\/a><\/strong><a href=\"https:\/\/www.osmosis.org\/ultimate-guide\/nclex-rn\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><u>Check out our&nbsp;NCLEX-RN Study Plan Guide!<\/u><\/strong><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\"><\/span>The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"B_Potassium_level_of_61_mEqL\"><\/span><strong>B. Potassium level of 6.1 mEq\/L<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong>&nbsp;TLS is a metabolic complication resulting from a rapid release of intracellular components, such as potassium, in response to chemotherapy. Potassium greater than 6 mEq\/L correlates with a diagnosis of TLS. Normal potassium levels are 3.5-5.1 mEq\/L.<a href=\"https:\/\/www.osmosis.org\/plans\/do?source_cta=navbar\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.osmosis.org\/plans\/do?source_cta=navbar\"><img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"250\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-09T131731.003.png?w=700\" alt=\"Osmosis sign up ad\" class=\"wp-image-1453\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-09T131731.003.png 700w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-09T131731.003.png?resize=300,107 300w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Main_takeaway\"><\/span>Main takeaway<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.osmosis.org\/learn\/Tumor_lysis_syndrome_(TLS):_Nursing_Process_(ADPIE)\" target=\"_blank\" rel=\"noreferrer noopener\">Tumor lysis syndrome (TLS)<\/a>&nbsp;is a metabolic complication that results in the rapid release of intracellular components such as phosphate, potassium, and uric acid into the blood due to chemotherapy. Diagnosis of TLS begins with history and clinical findings. A complete metabolic panel (CMP) will be drawn to assess for electrolyte imbalance. TLS is indicated by calcium less than 7 mg\/dL (normal levels are 8.4-10.6 mg\/dL), uric acid greater than 8 mg\/dL (normal levels are 2.0-7.0 mg\/dL), phosphorus greater than 6.5 mg\/dL (normal levels are 3.0-4.5 mg\/dL), and potassium greater than 6 mEq\/L (normal levels are 3.5-5.1 mEq\/L).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Incorrect_answer_explanations\"><\/span>Incorrect answer explanations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_Phosphorus_level_of_44_mgdL\"><\/span>A. Phosphorus level of 4.4 mg\/dL<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale<\/strong>: Although phosphorus is one of the intracellular components released from the cells during TLS, normal levels are 3.0-4.5 mg\/dL. Therefore, this is not consistent with TLS.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"C_Calcium_level_of_84_mgdL\"><\/span>C. Calcium level of 8.4 mg\/dL<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale<\/strong>: Although calcium is one of the intracellular components affected by TLS, normal levels are 8.4-10.6 mg\/dL. Therefore, this is not consistent with TLS.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"D_Uric_acid_level_of_69_mgdL\"><\/span>D. Uric acid level of 6.9 mg\/dL<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale<\/strong><strong>:&nbsp;<\/strong>Although uric acid is one of the intracellular components released from the cells during TLS, normal levels are 2.0-7.0 mg\/dL. Therefore, this is not consistent with TLS.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"References\"><\/span>References<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Lewis, S.L., Bucher, L., Heitkemper, M.M., &amp; Harding, M.M. &nbsp;(2020).&nbsp;<em><a href=\"https:\/\/evolve.elsevier.com\/cs\/product\/9780323551496?role=student\" target=\"_blank\" rel=\"noreferrer noopener\">Medical-surgical nursing: Assessment and management of clinical problems<\/a><\/em><em>&nbsp;<\/em>(11th ed.)<em>.&nbsp;<\/em>St. Louis, MO: Elsevier.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>________________________<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Want more NCLEX\u00ae-style practice questions? Try Osmosis today! Access your&nbsp;<a href=\"https:\/\/www.osmosis.org\/login?type=create\" target=\"_blank\" rel=\"noreferrer noopener\">free trial<\/a>&nbsp;and find out why millions of current and future clinicians and caregivers love learning with us.<\/em><\/strong><br><a href=\"https:\/\/www.osmosis.org\/plans\/do?source_cta=navbar\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><a href=\"https:\/\/www.osmosis.org\/plans\/do?source_cta=navbar\"><img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"250\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-09T140944.481.png\" alt=\"Osmosis sign up ad\" class=\"wp-image-1465\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-09T140944.481.png 700w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-09T140944.481.png?resize=300,107 300w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">NCLEX-RN\u00ae and NCLEX-PN\u00ae are registered trademarks of the National Council of State Boards of Nursing, Inc (NCSBN\u00ae). Osmosis is not affiliated with NCSBN.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a nurse reviewing laboratory results on an oncology unit.&nbsp; The nurse is reviewing the blood work drawn for a client on the oncology unit. The nurse should recognize which laboratory result correlates with a diagnosis of tumor lysis syndrome (TLS)? A. Phosphorus level of 4.4 mg\/dL B. [&hellip;]<\/p>\n","protected":false},"author":279,"featured_media":1464,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[20,29,1367,32],"tags":[],"class_list":["post-1463","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exam-prep","category-nclex","category-nclex-rn","category-nursing"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog\" \/>\n<meta property=\"og:description\" content=\"Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a nurse reviewing laboratory results on an oncology unit.&nbsp; The nurse is reviewing the blood work drawn for a client on the oncology unit. 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The nurse is reviewing the blood work drawn for a client on the oncology unit. The nurse should recognize which laboratory result correlates with a diagnosis of tumor lysis syndrome (TLS)? A. Phosphorus level of 4.4 mg\/dL B. 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