{"id":1524,"date":"2022-12-28T12:54:00","date_gmt":"2022-12-28T12:54:00","guid":{"rendered":"https:\/\/www.osmosis.org\/blog\/?p=1524"},"modified":"2025-10-01T11:40:31","modified_gmt":"2025-10-01T19:40:31","slug":"usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen","status":"publish","type":"post","link":"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen","title":{"rendered":"USMLE\u00ae Step 2 CK Question of the Day: Altered Mental State After \u201cOver-the-counter pain reliever\u201d and Prescription Hydrocodone-acetaminophen"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-center counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">In This Article<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#The_correct_answer_to_todays_USMLE%C2%AE_Step_2_CK_Question_is%E2%80%A6\" >The correct answer to today&#8217;s USMLE\u00ae Step 2 CK Question is&#8230;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#A_N-Acetylcysteine\" >A. N-Acetylcysteine<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#Incorrect_answer_explanations\" >Incorrect answer explanations<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#B_Activated_charcoal\" >B. Activated charcoal&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#C_Sodium_bicarbonate\" >C. Sodium bicarbonate<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#D_Orogastric_lavage\" >D. Orogastric lavage&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#E_Whole_bowel_irrigation\" >E. Whole bowel irrigation<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#Main_Explanation\" >Main Explanation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#Major_Takeaway\" >Major Takeaway<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\/#References\" >References<\/a><\/li><\/ul><\/nav><\/div>\n\n<p class=\"wp-block-paragraph\"><em><strong>Here&#8217;s another USMLE\u00ae Step 2 CK Question of the Day!&nbsp;Today&#8217;s case involves a 50-year-old man who took hydrocodone-acetaminophen for his knee pain. He has a history of chronic lower back pain and chronic alcohol use. His partner reported he was less responsive several hours after taking the medication. Can you figure it out?<\/strong><\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A 50-year-old man is brought to the emergency department by his partner for evaluation of altered mental status. His partner states the patient woke up today with knee pain, for which he took an &#8220;over-the-counter pain reliever&#8221; and his prescription hydrocodone-acetaminophen. Several hours later, the partner noticed he was less responsive and unaware of where he was. The patient has a history of chronic lower back pain and chronic alcohol use. On physical examination, the patient is not oriented and responds only to pain. The patient grimaces with palpation of the right upper quadrant. AST and ALT are 2136 and 2467 IU\/L, respectively. Which of the following is the most appropriate therapeutic treatment for this patient&#8217;s clinical condition?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. N-Acetylcysteine<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Activated charcoal&nbsp;<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. Sodium bicarbonate<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. Orogastric lavage&nbsp;<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>E. Whole bowel irrigation<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_correct_answer_to_todays_USMLE%C2%AE_Step_2_CK_Question_is%E2%80%A6\"><\/span><strong>The correct answer to today&#8217;s USMLE\u00ae Step 2 CK Question is&#8230;<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_N-Acetylcysteine\"><\/span><strong>A. N-Acetylcysteine<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Before we get to the Main Explanation, let&#8217;s see why the answer wasn&#8217;t B, C, D, or E. Skip to the bottom if you want to see the correct answer right away!<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Incorrect_answer_explanations\"><\/span>Incorrect answer explanations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Today&#8217;s incorrect answers are&#8230;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"B_Activated_charcoal\"><\/span><strong>B. Activated charcoal&nbsp;<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:<\/strong>&nbsp;Activated charcoal may be used to treat acetaminophen overdose when the patient is alert and protecting their airway, and ingestion is within one hour of presentation. Activated charcoal should be avoided in this patient due to the risk of aspiration injury.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"C_Sodium_bicarbonate\"><\/span>C. Sodium bicarbonate<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:<\/strong>&nbsp;Sodium bicarbonate is an alkaline solution that is used in the treatment of salicylates and tricyclic antidepressants toxicity. It has no role in the management of acetaminophen toxicity.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"D_Orogastric_lavage\"><\/span>D. Orogastric lavage&nbsp;<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:&nbsp;<\/strong>Orogastric lavage is not effective for the treatment of acetaminophen toxicity.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"E_Whole_bowel_irrigation\"><\/span>E. Whole bowel irrigation<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:<\/strong>&nbsp;Whole bowel irrigation, like orogastric lavage, is not effective for the treatment of acetaminophen toxicity.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Main_Explanation\"><\/span><strong>Main Explanation<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This patient presents with altered mental status, right upper quadrant tenderness, and elevated liver enzymes consistent with acute hepatic injury and encephalopathy secondary to acetaminophen overdose. Most cases of acetaminophen toxicity are due to intentional ingestion of large amounts of acetaminophen; however, some patients develop toxicity unintentionally via ingestion of acetaminophen from multiple sources or via underlying hepatic dysfunction (e.g., chronic alcohol use).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Acetaminophen metabolism at therapeutic doses occurs through glucuronidation and sulfation in the liver, which yields non-toxic products that are eliminated through urine. A minimal amount of acetaminophen is converted by CYP450 to the toxic N-acetyl-p-benzoquinone imine (NAPQI); however, this compound is quickly eliminated by combining it with the substrate glutathione.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In case of overdose, glucuronidation and sulfation pathways become saturated, leading to increased metabolism by CYP450 and production of NAPQI. The high amount of NAPQI depletes glutathione, with subsequent NAPQI accumulation, resulting in hepatic necrosis and acute liver failure.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">First-line treatment for acetaminophen toxicity is N-acetylcysteine (NAC). NAC is fully protective of the liver; it exerts its protective effects by replenishing glutathione, increasing detoxification of NAPQI, and thus preventing further hepatocyte injury and necrosis.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"848\" height=\"444\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/treatment-acetaminophen-overdose.png\" alt=\"acetaminophen overdose treatment\" class=\"wp-image-1526\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/treatment-acetaminophen-overdose.png 848w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/treatment-acetaminophen-overdose.png?resize=300,157 300w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/treatment-acetaminophen-overdose.png?resize=768,402 768w\" sizes=\"auto, (max-width: 848px) 100vw, 848px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Major_Takeaway\"><\/span><strong>Major Takeaway<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">N-acetylcysteine is the first-line treatment of acetaminophen toxicity. It replenishes glutathione in hepatocytes, thus increasing the metabolism of NAPQI and protecting the liver.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"References\"><\/span><strong>References<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Agrawal S, Khazaeni B.&nbsp;<em>Acetaminophen Toxicity<\/em>. [Updated 2020 Sep 15]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from:&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK441917\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK441917\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here&#8217;s another USMLE\u00ae Step 2 CK Question of the Day!&nbsp;Today&#8217;s case involves a 50-year-old man who took hydrocodone-acetaminophen for his knee pain. He has a history of chronic lower back pain and chronic alcohol use. His partner reported he was less responsive several hours after taking the medication. Can you figure it out? A 50-year-old [&hellip;]<\/p>\n","protected":false},"author":202,"featured_media":1525,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[27,20,45],"tags":[],"class_list":["post-1524","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine","category-exam-prep","category-step-2"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>USMLE\u00ae Step 2 CK Question of the Day: Altered Mental State After \u201cOver-the-counter pain reliever\u201d and Prescription Hydrocodone-acetaminophen - Osmosis Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"USMLE\u00ae Step 2 CK Question of the Day: Altered Mental State After \u201cOver-the-counter pain reliever\u201d and Prescription Hydrocodone-acetaminophen - Osmosis Blog\" \/>\n<meta property=\"og:description\" content=\"Here&#8217;s another USMLE\u00ae Step 2 CK Question of the Day!&nbsp;Today&#8217;s case involves a 50-year-old man who took hydrocodone-acetaminophen for his knee pain. He has a history of chronic lower back pain and chronic alcohol use. His partner reported he was less responsive several hours after taking the medication. Can you figure it out? A 50-year-old [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\" \/>\n<meta property=\"og:site_name\" content=\"Osmosis Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-12-28T12:54:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-01T19:40:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-altered-mental-state_5c198b.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1081\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Marina Horiates Kerekes, MD &amp; Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":[\"Article\",\"BlogPosting\"],\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\"},\"author\":{\"name\":\"Marina Horiates Kerekes, MD &amp; Team\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/c7e60a94ecf3ec6e6cfe4855957afafc\"},\"headline\":\"USMLE\u00ae Step 2 CK Question of the Day: Altered Mental State After \u201cOver-the-counter pain reliever\u201d and Prescription Hydrocodone-acetaminophen\",\"datePublished\":\"2022-12-28T12:54:00+00:00\",\"dateModified\":\"2025-10-01T19:40:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\"},\"wordCount\":629,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-altered-mental-state_5c198b.webp\",\"articleSection\":[\"Allopathic Medicine (MD)\",\"Exam Prep\",\"USMLE\u00ae Step 2\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\",\"url\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-altered-mental-state-after-over-the-counter-pain-reliever-and-prescription-hydrocodone-acetaminophen\",\"name\":\"USMLE\u00ae Step 2 CK Question of the Day: Altered Mental State After \u201cOver-the-counter pain reliever\u201d and Prescription Hydrocodone-acetaminophen - 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Medical history is remarkable for long-standing\u00a0Graves disease\u00a0and\u00a0gastroesophageal reflux disease. IV propranolol is initiated. Which additional medications should also be administered to this patient? 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Today's case involves a young woman who is experiencing unilateral headaches with photophobia. Can you prescribe a medication to help her feel better? 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Discover the intricacies of this procedure and identify\u2026","rel":"","context":"In &quot;Allopathic Medicine (MD)&quot;","block_context":{"text":"Allopathic Medicine (MD)","link":"https:\/\/www.osmosis.org\/blog\/category\/medicine"},"img":{"alt_text":"USMLE\u00ae Step 2 Question of the Day: Endoscopic repair","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/84.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/84.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/84.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/84.webp 2x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/1524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/users\/202"}],"replies":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/comments?post=1524"}],"version-history":[{"count":1,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/1524\/revisions"}],"predecessor-version":[{"id":1527,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/1524\/revisions\/1527"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media\/1525"}],"wp:attachment":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media?parent=1524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/categories?post=1524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/tags?post=1524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}