{"id":4049,"date":"2021-02-10T18:36:00","date_gmt":"2021-02-10T18:36:00","guid":{"rendered":"https:\/\/www.osmosis.org\/blog\/?p=4049"},"modified":"2025-10-01T11:42:40","modified_gmt":"2025-10-01T19:42:40","slug":"usmle-step-1-question-of-the-day-signs-of-end-organ-damage","status":"publish","type":"post","link":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage","title":{"rendered":"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-center counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">In This Article<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#The_correct_answer_to_todays_USMLE%C2%AE_Step_1_Question_is%E2%80%A6\" >The correct answer to today&#8217;s USMLE\u00ae Step 1 Question is&#8230;<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#B_Reticulocyte_count_of_6\" >B. Reticulocyte count of 6%<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#Incorrect_answer_explanations\" >Incorrect answer explanations<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#A_Platelet_count_of_250000%CE%BCL\" >A. Platelet count of 250,000\/\u03bcL &nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#C_Normal_levels_of_haptoglobin\" >C. Normal levels of haptoglobin<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#D_Direct_bilirubin_level_of_3_mgdL\" >D. Direct bilirubin level of 3 mg\/dL<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#E_Hematocrit_of_40\" >E. Hematocrit of 40%<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#Main_Explanation\" >Main Explanation&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#Major_Takeaway\" >Major Takeaway&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\/#References\" >References<\/a><\/li><\/ul><\/nav><\/div>\n\n<p class=\"wp-block-paragraph\"><strong><em>Each week, Osmosis shares a USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics and help you prepare for the boards. Today&#8217;s case involves a 64-year-old woman who&#8217;s experiencing headaches, vision disturbances, and reduced urine output. Can you figure out what the diagnosis could be?<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A 64-year-old woman presents to the emergency department because of decreased urine output and dark urine for the last 2 weeks. She also reports fatigue and a worsening headache associated with visual disturbance for the last 2 days. Her past medical history is significant for hypertension, but she states that she has not taken her medication for the past year. Her temperature is 37 \u00b0C (98.6 \u00b0F), pulse is 86\/min, respirations are 20\/min, and blood pressure is 222\/146 mmHg. Fundoscopic examination shows papilledema and retinal hemorrhages. A urine dipstick is positive for blood. Which of the following laboratory findings is also most likely to be present in this patient?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. Platelet count of 250,000\/\u03bcL &nbsp;<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Reticulocyte count of 6%<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. Normal levels of haptoglobin<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. Direct bilirubin level of 3 mg\/dL<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>E. Hematocrit of 40%<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Scroll down to find the answer!<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-embed-handler wp-block-embed-embed-handler wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Everybody loves Osmosis.org\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/kizbJZ9cdLg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.osmosis.org\/plans\" target=\"_blank\" rel=\"noreferrer noopener\"><u><em><strong>\u2192 Reinforce your understanding with more self-assessment items on Osmosis.<\/strong><\/em><\/u><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_correct_answer_to_todays_USMLE%C2%AE_Step_1_Question_is%E2%80%A6\"><\/span>The correct answer to today&#8217;s USMLE\u00ae Step 1 Question is&#8230;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"B_Reticulocyte_count_of_6\"><\/span><strong>B. Reticulocyte count of 6%<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Before we get to the&nbsp;<strong>Main Explanation<\/strong>, let&#8217;s look at the incorrect answer explanations. Skip to the bottom if you want to see the correct answer right away!<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Incorrect_answer_explanations\"><\/span>Incorrect answer explanations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The incorrect answers to today&#8217;s USMLE\u00ae Step 1 Question are&#8230;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_Platelet_count_of_250000%CE%BCL\"><\/span>A. Platelet count of 250,000\/\u03bcL &nbsp;<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:<\/strong>&nbsp;This patient with hypertensive emergency likely has&nbsp;<a href=\"https:\/\/www.osmosis.org\/learn\/Thrombotic_thrombocytopenic_purpura:_Foundations\" target=\"_blank\" rel=\"noreferrer noopener\">thrombotic microangiopathy<\/a>. She would be expected to have a decreased platelet count of less than 150,000\/\u03bcL due to platelet consumption.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"C_Normal_levels_of_haptoglobin\"><\/span>C. Normal levels of haptoglobin<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:<\/strong>&nbsp;This patient would be expected to have low haptoglobin levels of less than 50 mg\/dL due to&nbsp;intravascular hemolytic anemia. As hemolysis occurs, hemoglobin is released into the blood and binds to haptoglobin. Both proteins are removed from the blood together, and haptoglobin levels decrease.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"D_Direct_bilirubin_level_of_3_mgdL\"><\/span>D. Direct bilirubin level of 3 mg\/dL<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:<\/strong>&nbsp;This patient would be expected to have normal direct bilirubin levels of less than 0.3 mg\/dL. Indirect bilirubin levels would be elevated in this patient due to bleeding and hemolytic anemia.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"E_Hematocrit_of_40\"><\/span>E. Hematocrit of 40%<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incorrect:<\/strong>&nbsp;This patient with dark urine and urine dipstick positive for blood would be expected to have a&nbsp;<a href=\"https:\/\/www.osmosis.org\/learn\/Measuring_renal_plasma_flow_and_renal_blood_flow\" target=\"_blank\" rel=\"noreferrer noopener\">low hematocrit<\/a>&nbsp;of less than 37% due to hemolytic anemia. Normal hematocrit levels in women are 37\u201347% and in &nbsp;42\u201350% in men.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Main_Explanation\"><\/span><strong>Main Explanation&nbsp;<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This patient with a blood pressure of 222\/146 mmHg associated with signs of end-organ damage (severe headache, visual disturbance, as well as papilledema and retinal hemorrhages seen on fundoscopy) is most likely experiencing a&nbsp;hypertensive emergency. &nbsp;Hypertensive emergency is defined as the combination of severely elevated blood pressure (systolic \u2265180 mmHg and diastolic \u2265120 mmHg) and signs of end-organ damage, such as&nbsp;stroke,&nbsp;myocardial infarction,&nbsp;aortic dissection, retinal hemorrhages, and exudates,&nbsp;<a href=\"https:\/\/www.osmosis.org\/learn\/Acute_kidney_injury:_Clinical_practice\" target=\"_blank\" rel=\"noreferrer noopener\">acute kidney injury<\/a>, and&nbsp;<a href=\"https:\/\/www.osmosis.org\/learn\/Extrinsic_hemolytic_normocytic_anemia:_Pathology_review\" target=\"_blank\" rel=\"noreferrer noopener\">microangiopathic hemolytic anemia<\/a>.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This patient\u2019s decreased urine output and darker-than-normal urine indicate a resultant microangiopathic hemolytic anemia (MAHA). MAHA is a type of normocytic hemolytic anemia, defined as having a mean corpuscular volume (MCV) of 80-100 fL. In hypertensive emergencies, fibrinoid necrosis of blood vessels leads to endothelial damage, which causes vessel narrowing and the formation of platelet-rich microthrombi (causing&nbsp;<a href=\"https:\/\/www.osmosis.org\/learn\/Thrombocytopenia:_Clinical_practice\" target=\"_blank\" rel=\"noreferrer noopener\">thrombocytopenia<\/a>) within small vessels. This leads to RBC damage (hemolysis) as the cells pass through these obstructed blood vessels, causing the MAHA. The damaged RBCs can be seen as sheared erythrocyte fragments, or schistocytes, on peripheral blood smear. The resultant hemolytic anemia then presents with darkened urine, which is caused by hemoglobinuria and hemosiderinuria. This usually occurs a few days later when the renal tubular cells, which absorbed the hemoglobin, slough off into the urine. Hemolytic anemia also presents with elevated reticulocyte count due to a compensatory increase in erythrocyte production.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Hypertension- causes, symptoms, diagnosis, treatment, pathology\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/Qm5kB5X70oA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Major_Takeaway\"><\/span>Major Takeaway&nbsp;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Hypertensive emergency is defined as the combination of severely elevated blood pressure (systolic \u2265180 mmHg and diastolic \u2265120 mmHg) and signs of end-organ damage, such as microangiopathic hemolytic anemia (MAHA). MAHA is a type of normocytic hemolytic anemia characterized by the presence of schistocytes on peripheral blood smears. Common laboratory findings include normal MCV, decreased hemoglobin, decreased haptoglobin, and increased reticulocyte count.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"References\"><\/span>References<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/1752-1947-4-86\" target=\"_blank\" rel=\"noreferrer noopener\">Pica in iron deficiency: a case series<\/a>.<\/li>\n\n\n\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002571251630339X?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">Microcytic anemia: Differential Diagnosis and Management of Iron Deficiency Anemia<\/a>.<\/li>\n\n\n\n<li><a href=\"https:\/\/casereports.bmj.com\/content\/2017\/bcr-2017-220457\" target=\"_blank\" rel=\"noreferrer noopener\">Malignant hypertension as a rare cause of thrombotic microangiopathy<\/a>.<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK430721\/\" target=\"_blank\" rel=\"noreferrer noopener\">Thrombotic Thrombocytopenic Purpura<\/a>.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>_________________________<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Want more USMLE\u00ae Step 1 practice questions? Try Osmosis today! Access your&nbsp;<a href=\"https:\/\/www.osmosis.org\/login?type=create\" target=\"_blank\" rel=\"noreferrer noopener\">free trial<\/a>&nbsp;and find out why millions of current and future clinicians and caregivers love learning with us.<\/em><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.osmosis.org\/plans\"><img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"250\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/image_3c5ed6.png?w=700\" alt=\"\" class=\"wp-image-3931\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/image_3c5ed6.png 700w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/image_3c5ed6.png?resize=300,107 300w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>The United States Medical Licensing Examination (USMLE\u00ae) is a joint program of the Federation of State Medical Boards (FSMB\u00ae) and National Board of Medical Examiners (NBME\u00ae). Osmosis is not affiliated with NBME nor FSMB<\/em>.<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Each week, Osmosis shares a USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics and help you prepare for the boards. Today&#8217;s case involves a 64-year-old woman who&#8217;s experiencing headaches, vision disturbances, and reduced urine output. Can you figure out what the diagnosis could be? A 64-year-old woman presents to the emergency [&hellip;]<\/p>\n","protected":false},"author":202,"featured_media":4050,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[27,20,1369,44],"tags":[],"class_list":["post-4049","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine","category-exam-prep","category-step-1-questions","category-step-1"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage - Osmosis Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage - Osmosis Blog\" \/>\n<meta property=\"og:description\" content=\"Each week, Osmosis shares a USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics and help you prepare for the boards. Today&#8217;s case involves a 64-year-old woman who&#8217;s experiencing headaches, vision disturbances, and reduced urine output. Can you figure out what the diagnosis could be? A 64-year-old woman presents to the emergency [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\" \/>\n<meta property=\"og:site_name\" content=\"Osmosis Blog\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-10T18:36:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-01T19:42:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1081\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Marina Horiates Kerekes, MD &amp; Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":[\"Article\",\"BlogPosting\"],\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\"},\"author\":{\"name\":\"Marina Horiates Kerekes, MD &amp; Team\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/c7e60a94ecf3ec6e6cfe4855957afafc\"},\"headline\":\"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage\",\"datePublished\":\"2021-02-10T18:36:00+00:00\",\"dateModified\":\"2025-10-01T19:42:40+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\"},\"wordCount\":845,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp\",\"articleSection\":[\"Allopathic Medicine (MD)\",\"Exam Prep\",\"USMLE Step 1\",\"USMLE\u00ae Step 1\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\",\"url\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\",\"name\":\"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage - Osmosis Blog\",\"isPartOf\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp\",\"datePublished\":\"2021-02-10T18:36:00+00:00\",\"dateModified\":\"2025-10-01T19:42:40+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage\",\"url\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp\",\"contentUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp\",\"width\":1081,\"height\":1080},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.osmosis.org\/blog\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#website\",\"url\":\"https:\/\/www.osmosis.org\/blog\/\",\"name\":\"Osmosis Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.osmosis.org\/blog\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\",\"name\":\"Osmosis Blog\",\"url\":\"https:\/\/www.osmosis.org\/blog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png\",\"contentUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png\",\"width\":1276,\"height\":596,\"caption\":\"Osmosis Blog\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/c7e60a94ecf3ec6e6cfe4855957afafc\",\"name\":\"Marina Horiates Kerekes, MD &amp; Team\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c4eaddbf095676223204097f8973e0eed2b2b435a8c32f8f6b8c06da77819aa6?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c4eaddbf095676223204097f8973e0eed2b2b435a8c32f8f6b8c06da77819aa6?s=96&d=mm&r=g\",\"caption\":\"Marina Horiates Kerekes, MD &amp; Team\"},\"description\":\"Authors: Marina Horiates Kerekes, MD &amp; Osmosis Question Writing Team\",\"url\":\"https:\/\/www.osmosis.org\/blog\/author\/marinahoriateskerekesandteam\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage - Osmosis Blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage","og_locale":"en_US","og_type":"article","og_title":"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage - Osmosis Blog","og_description":"Each week, Osmosis shares a USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics and help you prepare for the boards. Today&#8217;s case involves a 64-year-old woman who&#8217;s experiencing headaches, vision disturbances, and reduced urine output. Can you figure out what the diagnosis could be? A 64-year-old woman presents to the emergency [&hellip;]","og_url":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage","og_site_name":"Osmosis Blog","article_published_time":"2021-02-10T18:36:00+00:00","article_modified_time":"2025-10-01T19:42:40+00:00","og_image":[{"width":1081,"height":1080,"url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp","type":"image\/webp"}],"author":"Marina Horiates Kerekes, MD &amp; Team","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":["Article","BlogPosting"],"@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#article","isPartOf":{"@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage"},"author":{"name":"Marina Horiates Kerekes, MD &amp; Team","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/c7e60a94ecf3ec6e6cfe4855957afafc"},"headline":"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage","datePublished":"2021-02-10T18:36:00+00:00","dateModified":"2025-10-01T19:42:40+00:00","mainEntityOfPage":{"@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage"},"wordCount":845,"commentCount":0,"publisher":{"@id":"https:\/\/www.osmosis.org\/blog\/#organization"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage"},"thumbnailUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp","articleSection":["Allopathic Medicine (MD)","Exam Prep","USMLE Step 1","USMLE\u00ae Step 1"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage","url":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage","name":"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage - Osmosis Blog","isPartOf":{"@id":"https:\/\/www.osmosis.org\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage"},"thumbnailUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp","datePublished":"2021-02-10T18:36:00+00:00","dateModified":"2025-10-01T19:42:40+00:00","breadcrumb":{"@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#primaryimage","url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp","contentUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp","width":1081,"height":1080},{"@type":"BreadcrumbList","@id":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-signs-of-end-organ-damage#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.osmosis.org\/blog"},{"@type":"ListItem","position":2,"name":"USMLE\u00ae Step 1 Question of the Day: Signs of End Organ Damage"}]},{"@type":"WebSite","@id":"https:\/\/www.osmosis.org\/blog\/#website","url":"https:\/\/www.osmosis.org\/blog\/","name":"Osmosis Blog","description":"","publisher":{"@id":"https:\/\/www.osmosis.org\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.osmosis.org\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.osmosis.org\/blog\/#organization","name":"Osmosis Blog","url":"https:\/\/www.osmosis.org\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png","contentUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png","width":1276,"height":596,"caption":"Osmosis Blog"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/c7e60a94ecf3ec6e6cfe4855957afafc","name":"Marina Horiates Kerekes, MD &amp; Team","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c4eaddbf095676223204097f8973e0eed2b2b435a8c32f8f6b8c06da77819aa6?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c4eaddbf095676223204097f8973e0eed2b2b435a8c32f8f6b8c06da77819aa6?s=96&d=mm&r=g","caption":"Marina Horiates Kerekes, MD &amp; Team"},"description":"Authors: Marina Horiates Kerekes, MD &amp; Osmosis Question Writing Team","url":"https:\/\/www.osmosis.org\/blog\/author\/marinahoriateskerekesandteam"}]}},"jetpack_featured_media_url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-signs-of-end-organ-damage.webp","jetpack-related-posts":[{"id":3441,"url":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-urethritis","url_meta":{"origin":4049,"position":0},"title":"USMLE\u00ae Step 1 Question of the Day: Urethritis","author":"Marina Horiates Kerekes, MD &amp; Team","date":"December 22, 2021","format":false,"excerpt":"Each week, Osmosis shares a USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics. Today's case focuses on a 26-year-old man with penile discharge and urination pain after engaging in unprotected sexual intercourse.\u00a0Can you figure it out? A 26-year-old man presents to his primary care physician with\u2026","rel":"","context":"In &quot;Allopathic Medicine (MD)&quot;","block_context":{"text":"Allopathic Medicine (MD)","link":"https:\/\/www.osmosis.org\/blog\/category\/medicine"},"img":{"alt_text":"USMLE\u00ae Step 1 Question of the Day: Urethritis","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T132226.154.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T132226.154.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T132226.154.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T132226.154.webp 2x"},"classes":[]},{"id":3146,"url":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-urinary-incontinence","url_meta":{"origin":4049,"position":1},"title":"USMLE\u00ae Step 1 Question of the Day: Urinary Incontinence","author":"Marina Horiates Kerekes, MD &amp; Team","date":"May 19, 2021","format":false,"excerpt":"Each week, Osmosis shares a USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics. Today's case involves a 55 year-old female patient with urinary incontinence. Her past medical history is notable for type 2 diabetes mellitus and hypertension. Can you figure it out? A 55 year-old female\u2026","rel":"","context":"In &quot;Allopathic Medicine (MD)&quot;","block_context":{"text":"Allopathic Medicine (MD)","link":"https:\/\/www.osmosis.org\/blog\/category\/medicine"},"img":{"alt_text":"USMLE\u00ae Step 1 Question of the Day: Urinary Incontinence","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T073325.938.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T073325.938.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T073325.938.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T073325.938.webp 2x"},"classes":[]},{"id":1326,"url":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-increased-urination-and-thirst","url_meta":{"origin":4049,"position":2},"title":"USMLE\u00ae Step 1 Question of the Day: Increased Urination and Thirst","author":"Marina Horiates Kerekes, MD &amp; Team","date":"August 3, 2022","format":false,"excerpt":"This week, we are sharing another USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics.\u00a0Today's case involves a 33-year-old man with increased urination and constant thirst.\u00a0Can you figure it out? A 33-year-old man comes to the emergency department because of increased urination and constant thirst despite drinking\u2026","rel":"","context":"In &quot;Allopathic Medicine (MD)&quot;","block_context":{"text":"Allopathic Medicine (MD)","link":"https:\/\/www.osmosis.org\/blog\/category\/medicine"},"img":{"alt_text":"","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-increased-urination-and-thrirst.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-increased-urination-and-thrirst.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-increased-urination-and-thrirst.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/usmle-increased-urination-and-thrirst.webp 2x"},"classes":[]},{"id":3222,"url":"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-urgency-incontinence","url_meta":{"origin":4049,"position":3},"title":"USMLE\u00ae Step 2 CK Question of the Day: Urgency Incontinence","author":"Marina Horiates Kerekes, MD &amp; Team","date":"September 15, 2021","format":false,"excerpt":"We're back with a USMLE\u00ae Step 2 CK Question of the Day!\u00a0Today's case involves a 31-year-old woman with urinary incontinence. Which of the following interventions is used in treating this patient\u2019s condition? A 31-year-old woman has come to an outpatient clinic for urinary incontinence over the past week. Since the\u2026","rel":"","context":"In &quot;Allopathic Medicine (MD)&quot;","block_context":{"text":"Allopathic Medicine (MD)","link":"https:\/\/www.osmosis.org\/blog\/category\/medicine"},"img":{"alt_text":"USMLE\u00ae Step 2 CK Question of the Day: Urgency Incontinence","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T085952.318.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T085952.318.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T085952.318.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T085952.318.webp 2x"},"classes":[]},{"id":9426,"url":"https:\/\/www.osmosis.org\/blog\/usmle-step-2-ck-question-of-the-day-dysuria","url_meta":{"origin":4049,"position":4},"title":"USMLE\u00ae Step 2 CK Question of the Day:\u00a0Dysuria","author":"Rowan Bell, MD &amp; Marina Horiates Kerekes, MD","date":"March 23, 2026","format":false,"excerpt":"Follow the case of a 30-year-old woman with four days of dysuria, urgency, and suprapubic tenderness as clinicians review history, exam findings, and urinalysis results to navigate the differential and why certain tests guide decision-making.","rel":"","context":"In &quot;Allopathic Medicine (MD)&quot;","block_context":{"text":"Allopathic Medicine (MD)","link":"https:\/\/www.osmosis.org\/blog\/category\/medicine"},"img":{"alt_text":"USMLE Step 2 Question of the Day: Dysuria","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/03\/USMLE-step-2-question-of-the-day-dysuria.jpg","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/03\/USMLE-step-2-question-of-the-day-dysuria.jpg 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/03\/USMLE-step-2-question-of-the-day-dysuria.jpg 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/03\/USMLE-step-2-question-of-the-day-dysuria.jpg 2x"},"classes":[]},{"id":648,"url":"https:\/\/www.osmosis.org\/blog\/usmle-step-1-question-of-the-day-frequent-urination-diagnosis","url_meta":{"origin":4049,"position":5},"title":"USMLE\u00ae Step 1 Question of the Day: Frequent Urination Diagnosis","author":"Marina Horiates Kerekes, MD &amp; Team","date":"January 13, 2021","format":false,"excerpt":"Each week, Osmosis shares a USMLE\u00ae Step 1-style practice question to test your knowledge of medical topics. Today's case involves a young boy whose worsening issues with thirst and frequent urination are worrying his parents. Can you make the correct diagnosis and help this family out? An 8-year-old boy is\u2026","rel":"","context":"In &quot;Allopathic Medicine (MD)&quot;","block_context":{"text":"Allopathic Medicine (MD)","link":"https:\/\/www.osmosis.org\/blog\/category\/medicine"},"img":{"alt_text":"USMLE\u00ae Step 1 Question of the Day: Frequent Urination Diagnosis","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/25.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/25.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/25.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/25.webp 2x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/4049","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/users\/202"}],"replies":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/comments?post=4049"}],"version-history":[{"count":3,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/4049\/revisions"}],"predecessor-version":[{"id":6772,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/4049\/revisions\/6772"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media\/4050"}],"wp:attachment":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media?parent=4049"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/categories?post=4049"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/tags?post=4049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}