{"id":5027,"date":"2024-12-04T04:27:00","date_gmt":"2024-12-04T12:27:00","guid":{"rendered":"https:\/\/www.osmosis.org\/blog\/?p=5027"},"modified":"2026-03-20T13:50:47","modified_gmt":"2026-03-20T21:50:47","slug":"nclex-question-of-the-day-pku","status":"publish","type":"post","link":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-pku","title":{"rendered":"NCLEX-RN\u00ae Question of the Day: Phenylketonuria (PKU)"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-center counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">In This Article<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-pku\/#The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\" >The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-pku\/#Major_Takeaway\" >Major Takeaway<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-pku\/#Incorrect_Answer_Explanations\" >Incorrect Answer Explanations<\/a><\/li><\/ul><\/nav><\/div>\n\n<p class=\"wp-block-paragraph\"><strong><em>Prepare for NCLEX success with today&#8217;s question: Learn how phenylalanine is acquired in a pediatric client with phenylketonuria (PKU). Can you identify the correct mechanism?<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The nurse in the primary care office is educating the caregivers of a pediatric client with phenylketonuria (PKU). By which mechanism is phenylalanine acquired?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. Through the conversion of tyrosine<br><br>B. Through the consumption of proteins<br><br>C. Through ingestion of carbohydrates<br><br>D. Through metabolism by the sympathetic nervous system<br><\/strong><em>Scroll down for the correct answer!<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\"><\/span>The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Through the consumption of proteins<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Rationale: Phenylalanine is an essential amino acid, meaning that it must be acquired through the consumption of protein. The body cannot make or store phenylalanine, so excess may be converted into another compound.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Major_Takeaway\"><\/span>Major Takeaway<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Amino acids are the basic building blocks that make up proteins. Phenylalanine is one of the essential amino acids, meaning the human body cannot make it, so it must be acquired through protein in the diet. Since the body cannot store amino acids, any excess amino acids are converted into glucose or ketones to be used for energy. Normally, phenylalanine is converted into the amino acid tyrosine by the enzyme phenylalanine hydroxylase with the help of a cofactor called tetrahydrobiopterin (BH4). Tyrosine is then made into several other products, including dopamine and serotonin, which are neurotransmitters that neurons use to communicate, as well as norepinephrine and epinephrine, which are also neurotransmitters and hormones used by the sympathetic nervous system.&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter is-resized\"><img decoding=\"async\" src=\"https:\/\/osmose-it.s3.amazonaws.com\/xfB4NMspSj630PAA-Nb_-bqATPCCsdWn\/_.png\" alt=\"Amino Acids\n- Basic building blocks that make up proteins\nPhenylalanine\n- Essential amino acid\n- Must be acquired through protein in a diet\nBody cannot store amino acids\n- Excess amino acids converted to glucose or ketones\n- Phenylalanine Hydroxylase + Tetrahydrobiopterin --&gt; Tyrosine --&gt; Dopamine, serotonin, norepinephrine, Epinephrine\" style=\"width:513px;height:auto\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Incorrect_Answer_Explanations\"><\/span>Incorrect Answer Explanations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. Through the conversion of tyrosine<br><\/strong><br><strong>Rationale:<\/strong>&nbsp;Tyrosine is an amino acid; although phenylalanine can be converted into tyrosine, it is not acquired through the transformation of tyrosine.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. Through ingestion of carbohydrates<br><\/strong><br><strong>Rationale:<\/strong>&nbsp;Phenylalanine is not acquired through this mechanism as carbohydrates do not contain phenylalanine.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. Through metabolism by the sympathetic nervous system<br><\/strong><br><strong>Rationale:<\/strong>&nbsp;The sympathetic nervous system utilizes neurotransmitters, which can be made from phenylalanine. However, the production of phenylalanine does not involve the sympathetic nervous system.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.osmosis.org\/plans\/rn\" target=\"_blank\" rel=\"noreferrer noopener\"><img decoding=\"async\" src=\"https:\/\/osmose-it.s3.amazonaws.com\/piwT1Bc2SrWcF5sQaugzNyZCQCyeELHo\/_.png\" alt=\"\"\/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Want more NCLEX\u00ae-style practice questions? Try Osmosis by Elsevier today! Access your&nbsp;<a href=\"https:\/\/www.osmosis.org\/login?type=create\" target=\"_blank\" rel=\"noreferrer noopener\">free trial<\/a>&nbsp;and discover why millions of current and future clinicians and caregivers love learning with us.<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prepare for NCLEX success with today&#8217;s question: Learn how phenylalanine is acquired in a pediatric client with phenylketonuria (PKU). Can you identify the correct mechanism? The nurse in the primary care office is educating the caregivers of a pediatric client with phenylketonuria (PKU). By which mechanism is phenylalanine acquired?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; A. Through the conversion of tyrosine [&hellip;]<\/p>\n","protected":false},"author":279,"featured_media":5028,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[20,29,1367,32],"tags":[],"class_list":["post-5027","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exam-prep","category-nclex","category-nclex-rn","category-nursing"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NCLEX-RN\u00ae Question of the Day: Phenylketonuria (PKU) - Osmosis Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-pku\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NCLEX-RN\u00ae Question of the Day: Phenylketonuria (PKU) - Osmosis Blog\" \/>\n<meta property=\"og:description\" content=\"Prepare for NCLEX success with today&#8217;s question: Learn how phenylalanine is acquired in a pediatric client with phenylketonuria (PKU). Can you identify the correct mechanism? The nurse in the primary care office is educating the caregivers of a pediatric client with phenylketonuria (PKU). By which mechanism is phenylalanine acquired?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; A. 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