{"id":7308,"date":"2025-08-20T00:01:00","date_gmt":"2025-08-20T08:01:00","guid":{"rendered":"https:\/\/www.osmosis.org\/blog\/?p=7308"},"modified":"2026-03-20T13:49:50","modified_gmt":"2026-03-20T21:49:50","slug":"nclex-question-of-the-day-femur-fracture","status":"publish","type":"post","link":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-femur-fracture","title":{"rendered":"NCLEX-RN\u00ae Question of the Day: Femur fracture"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-center counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">In This Article<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-femur-fracture\/#The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\" >The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-femur-fracture\/#Main_Takeaway\" >Main Takeaway<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-femur-fracture\/#Incorrect_Answer_Explanations\" >Incorrect Answer Explanations<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-femur-fracture\/#Want_to_learn_more_about_this_topic\" >Want to learn more about this topic?<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n<p class=\"wp-block-paragraph\"><strong><em>Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a femur fracture. Do you know the answer? Let&#8217;s find out!<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The nurse in the medical surgical unit is caring for a patient with a pathological femur fracture. While reviewing the patient\u2019s home medication list, the nurse recognizes which prescription can increase the risk of fractures?&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Home Prescriptions<\/strong>&nbsp;<\/td><\/tr><tr><td>Methylprednisolone 20mg PO once daily&nbsp;<\/td><\/tr><tr><td>Vitamin D3 50,000 IU PO once weekly<\/td><\/tr><tr><td>Clopidogrel 75 mg PO once daily&nbsp;<\/td><\/tr><tr><td>Disulfiram 500 mg PO once daily&nbsp;<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. \u202fMethylprednisolone<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Vitamin D3<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">C. <strong>Clopidogrel<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. Disulfiram<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><em>Scroll down for the correct answer!<\/em><\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-embed-handler wp-block-embed-embed-handler wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Nurses Learn by Osmosis.org\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/kGJCkPfFypA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.osmosis.org\/ultimate-guide\/nclex-rn\" target=\"_blank\" rel=\"noreferrer noopener\"><strong><u>Check out our&nbsp;NCLEX-RN Study Plan Guide!<\/u><\/strong><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\"><\/span>The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A.\u202fMethylprednisolone<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Risk for fractures increases due to long-term use of glucocorticoid medications, such as methylprednisolone. Glucocorticoids can cause pathological fractures because they decrease osteoblast activity and increase osteoclast activity.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Main_Takeaway\"><\/span>Main Takeaway<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Risk for fractures increases due to factors that weaken the bone, like smoking, alcohol use, vitamin D deficiency, and long-term use of glucocorticoid medications. Also, advanced age and underlying conditions like osteoporosis increase the risk of fractures. \u202fGlucocorticoids, like methylprednisolone, can cause pathological fractures because they decrease osteoblast activity and increase osteoclast activity.&nbsp;&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"975\" height=\"561\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_65e737.png\" alt=\"~ Smoking\n~ Alcohol use\n~ Vitamin D deficiency\n~ Long-term use of glucocorticoid medications\n~ Advanced age\n~ Underlying conditions (e.g., Osteoporosis)\" class=\"wp-image-7310\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_65e737.png 975w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_65e737.png?resize=300,173 300w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_65e737.png?resize=768,442 768w\" sizes=\"auto, (max-width: 975px) 100vw, 975px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Incorrect_Answer_Explanations\"><\/span>Incorrect Answer Explanations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Vitamin D3<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Vitamin D supplements do not increase the risk of fractures. Instead, having a vitamin D deficiency can increase the risk of fractures.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. Clopidogrel<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Clopidogrel does not increase the risk of fractures. It is a platelet inhibitor which can increase bleeding risk.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. Disulfiram<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Disulfiram does not increase the risk of fractures. This is a medication mainly used to treat chronic alcoholism, which can increase the risk of fractures.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Want_to_learn_more_about_this_topic\"><\/span>Want to learn more about this topic?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Watch the Osmosis video: <a href=\"https:\/\/www.osmosis.org\/learn\/Hip_fractures:_Nursing\">Hip fractures: Nursing<\/a><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.osmosis.org\/plans\"><img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"250\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/12\/Blog_Display_Ads_RN2_2023.png?w=700\" alt=\"\" class=\"wp-image-4977\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/12\/Blog_Display_Ads_RN2_2023.png 700w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/12\/Blog_Display_Ads_RN2_2023.png?resize=300,107 300w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Want more NCLEX\u00ae-style practice questions? Try Osmosis today! Access your&nbsp;<a href=\"https:\/\/www.osmosis.org\/create\" target=\"_blank\" rel=\"noreferrer noopener\">free trial<\/a>&nbsp;and find out why millions of current and future clinicians and caregivers love learning with us.<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Test your knowledge on medications that increase fracture risk. Which drug affects bone remodeling and raises the chance of pathological fractures?<\/p>\n","protected":false},"author":279,"featured_media":7311,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[20,29,1367,1366,32],"tags":[1303,1305,1299,1301,1304,1298,244,815,1302,1300],"class_list":["post-7308","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exam-prep","category-nclex","category-nclex-rn","category-questions","category-nursing","tag-bone-health","tag-clopidogrel","tag-disulfiram","tag-fracture-risk","tag-glucocorticoids","tag-methylprednisolone","tag-nclex-rn","tag-nursing-pharmacology","tag-osteoporosis","tag-vitamin-d"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NCLEX-RN\u00ae Question of the Day: Femur fracture - Osmosis Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-femur-fracture\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NCLEX-RN\u00ae Question of the Day: Femur fracture - Osmosis Blog\" \/>\n<meta property=\"og:description\" content=\"Test your knowledge on medications that increase fracture risk. 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