{"id":7314,"date":"2025-08-27T00:01:00","date_gmt":"2025-08-27T08:01:00","guid":{"rendered":"https:\/\/www.osmosis.org\/blog\/?p=7314"},"modified":"2026-03-20T13:54:31","modified_gmt":"2026-03-20T21:54:31","slug":"nclex-question-of-the-day-leukemic-blast-cells","status":"publish","type":"post","link":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells","title":{"rendered":"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-center counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">In This Article<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\/#The_correct_answer_to_todays_NCLEX-PN%C2%AE_Question_is%E2%80%A6\" >The correct answer to today&#8217;s NCLEX-PN\u00ae Question is&#8230;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\/#Main_Takeaway\" >Main Takeaway<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\/#Incorrect_Answer_Explanations\" >Incorrect Answer Explanations<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\/#Want_to_learn_more_about_this_topic\" >Want to learn more about this topic?<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n<p class=\"wp-block-paragraph\"><strong><em>Today&#8217;s NCLEX-PN\u00ae question of the day focuses on leukemic blast cells. Do you know the answer? Let&#8217;s find out!<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The nurse in the emergency department is caring for a patient with leukemia. Which clinical finding is related to the rapid proliferation and destruction of leukemic blast cells?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. Diarrhea<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Weight loss<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. Epistaxis<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">D. <strong>Hepatosplenomegaly<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><em>Scroll down for the correct answer!<\/em><\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-embed-handler wp-block-embed-embed-handler wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Nurses Learn by Osmosis.org\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/kGJCkPfFypA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_correct_answer_to_todays_NCLEX-PN%C2%AE_Question_is%E2%80%A6\"><\/span>The correct answer to today&#8217;s NCLEX-PN\u00ae Question is&#8230;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>B. Weight loss<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Hypermetabolism related to rapid proliferation and destruction of leukemic blast cells can manifest as weight loss.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Main_Takeaway\"><\/span>Main Takeaway<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Clinical manifestations of leukemia are primarily related to bone marrow failure. Anemia can produce symptoms like pallor, fatigue, and shortness of breath; thrombocytopenia can cause problems with clotting like excessive bruising, epistaxis, and hematuria; and with leukopenia, there is immune dysfunction and increased risk of infections, which can manifest as fever and fatigue. Additionally, infiltration of blast cells into other body tissues can cause hepatosplenomegaly and lymphadenopathy, as well as bone or joint pain; and hypermetabolism related to rapid proliferation and destruction of leukemic blast cells can manifest as fever and unintentional weight loss. Finally, since the leukemic blast cells die quickly, uric acid builds up in the blood, which can cause hyperuricemia.&nbsp;&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"975\" height=\"521\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_bb7d6c.png\" alt=\"CLINICAL MANIFESTATIONS\nInfiltration of blast cells into other body tissues\n- Hepatosplenomegaly\n- Lymphadenopathy\n- Bone or joint pain\n\nHypermetabolism\n(Rapid proliferation and destructions of blast cells)\n- Fever\n- Unintentional weight loss\n- Uric acid builds up in blood &quot;Hyperuricemia\" class=\"wp-image-7317\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_bb7d6c.png 975w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_bb7d6c.png?resize=300,160 300w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/image_bb7d6c.png?resize=768,410 768w\" sizes=\"auto, (max-width: 975px) 100vw, 975px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Incorrect_Answer_Explanations\"><\/span>Incorrect Answer Explanations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. Diarrhea<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Diarrhea is not a clinical finding associated with the rapid proliferation and destruction of leukemic blast cells.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. Epistaxis<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Although patients with leukemia can develop epistaxis, it is not related to the rapid proliferation and destruction of leukemic blast cells. Instead, thrombocytopenia from leukemia can cause problems with clotting like epistaxis, or nose bleeds.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. Hepatosplenomegaly<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong> Although patients with leukemia can develop hepatosplenomegaly, it is not related to the rapid proliferation and destruction of leukemic blast cells. Instead, infiltration of blast cells into the liver and spleen can cause hepatosplenomegaly.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Want_to_learn_more_about_this_topic\"><\/span>Want to learn more about this topic?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Watch the Osmosis video: <a href=\"Leukemia: Nursing pathophysiology\">Leukemia: Nursing pathophysiology<\/a><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.osmosis.org\/create\"><img loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"250\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/Blog_Display_Ads_RN1_2023_535910.png?w=700\" alt=\"\" class=\"wp-image-5083\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/Blog_Display_Ads_RN1_2023_535910.png 700w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/Blog_Display_Ads_RN1_2023_535910.png?resize=300,107 300w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Want more NCLEX-PN\u00ae-style practice questions? Try Osmosis today! Access your&nbsp;<a href=\"https:\/\/www.osmosis.org\/create\" target=\"_blank\" rel=\"noreferrer noopener\">free trial<\/a>&nbsp;and find out why millions of current and future clinicians and caregivers love learning with us.<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Explore a leukemia case focusing on signs linked to leukemic blast cell activity. Which clinical finding best reflects rapid cell proliferation and destruction?<\/p>\n","protected":false},"author":279,"featured_media":7316,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[20,867,29,1368,1366],"tags":[1310,1308,1312,1289,1309,1311,1279,245,1307,1306],"class_list":["post-7314","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exam-prep","category-lpn","category-nclex","category-nclex-pn","category-questions","tag-epistaxis","tag-hepatosplenomegaly","tag-hypermetabolism","tag-leukemia","tag-leukemia-symptoms","tag-leukemic-blast-cells","tag-nclex-lpn","tag-nursing-education","tag-thrombocytopenia","tag-weight-loss"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells - Osmosis Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells - Osmosis Blog\" \/>\n<meta property=\"og:description\" content=\"Explore a leukemia case focusing on signs linked to leukemic blast cell activity. Which clinical finding best reflects rapid cell proliferation and destruction?\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\" \/>\n<meta property=\"og:site_name\" content=\"Osmosis Blog\" \/>\n<meta property=\"article:published_time\" content=\"2025-08-27T08:01:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-20T21:54:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":[\"Article\",\"BlogPosting\"],\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\"},\"author\":{\"name\":\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158\"},\"headline\":\"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells\",\"datePublished\":\"2025-08-27T08:01:00+00:00\",\"dateModified\":\"2026-03-20T21:54:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\"},\"wordCount\":367,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg\",\"keywords\":[\"epistaxis\",\"hepatosplenomegaly\",\"hypermetabolism\",\"leukemia\",\"leukemia symptoms\",\"leukemic blast cells\",\"NCLEX-LPN\",\"nursing education\",\"thrombocytopenia\",\"weight loss\"],\"articleSection\":[\"Exam Prep\",\"LPN (Licensed Practical Nursing)\",\"NCLEX\",\"NCLEX-LPN\",\"Questions of the Day\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\",\"url\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\",\"name\":\"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells - Osmosis Blog\",\"isPartOf\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg\",\"datePublished\":\"2025-08-27T08:01:00+00:00\",\"dateModified\":\"2026-03-20T21:54:31+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage\",\"url\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg\",\"contentUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg\",\"width\":1080,\"height\":1080,\"caption\":\"NCLEX LPN Question of the day leukemic blast cells\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.osmosis.org\/blog\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#website\",\"url\":\"https:\/\/www.osmosis.org\/blog\/\",\"name\":\"Osmosis Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.osmosis.org\/blog\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\",\"name\":\"Osmosis Blog\",\"url\":\"https:\/\/www.osmosis.org\/blog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png\",\"contentUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png\",\"width\":1276,\"height\":596,\"caption\":\"Osmosis Blog\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158\",\"name\":\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g\",\"caption\":\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\"},\"description\":\"Author\/Reviewer Paige Randall, PhD, MS, RN, CEN, CNE, has been a Registered Nurse for more than a decade and has a clinical background in cardiac, emergency nursing, and nursing education Elizabeth Lucas, EdD, RN, CNE, has been a Registered Nurse since 2008 with a clinical background in oncology working in a Medical Oncology Unit, a Critical Care Bone Marrow Transplant Unit, and a Hematology\/Oncology Clinic.\",\"url\":\"https:\/\/www.osmosis.org\/blog\/author\/paigeandlizqotd\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells - Osmosis Blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells","og_locale":"en_US","og_type":"article","og_title":"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells - Osmosis Blog","og_description":"Explore a leukemia case focusing on signs linked to leukemic blast cell activity. Which clinical finding best reflects rapid cell proliferation and destruction?","og_url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells","og_site_name":"Osmosis Blog","article_published_time":"2025-08-27T08:01:00+00:00","article_modified_time":"2026-03-20T21:54:31+00:00","og_image":[{"width":1080,"height":1080,"url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg","type":"image\/jpeg"}],"author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":["Article","BlogPosting"],"@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#article","isPartOf":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells"},"author":{"name":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158"},"headline":"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells","datePublished":"2025-08-27T08:01:00+00:00","dateModified":"2026-03-20T21:54:31+00:00","mainEntityOfPage":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells"},"wordCount":367,"commentCount":0,"publisher":{"@id":"https:\/\/www.osmosis.org\/blog\/#organization"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage"},"thumbnailUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg","keywords":["epistaxis","hepatosplenomegaly","hypermetabolism","leukemia","leukemia symptoms","leukemic blast cells","NCLEX-LPN","nursing education","thrombocytopenia","weight loss"],"articleSection":["Exam Prep","LPN (Licensed Practical Nursing)","NCLEX","NCLEX-LPN","Questions of the Day"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells","url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells","name":"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells - Osmosis Blog","isPartOf":{"@id":"https:\/\/www.osmosis.org\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage"},"thumbnailUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg","datePublished":"2025-08-27T08:01:00+00:00","dateModified":"2026-03-20T21:54:31+00:00","breadcrumb":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#primaryimage","url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg","contentUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg","width":1080,"height":1080,"caption":"NCLEX LPN Question of the day leukemic blast cells"},{"@type":"BreadcrumbList","@id":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-leukemic-blast-cells#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.osmosis.org\/blog"},{"@type":"ListItem","position":2,"name":"NCLEX-LPN\u00ae Question of the Day: Leukemic blast cells"}]},{"@type":"WebSite","@id":"https:\/\/www.osmosis.org\/blog\/#website","url":"https:\/\/www.osmosis.org\/blog\/","name":"Osmosis Blog","description":"","publisher":{"@id":"https:\/\/www.osmosis.org\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.osmosis.org\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.osmosis.org\/blog\/#organization","name":"Osmosis Blog","url":"https:\/\/www.osmosis.org\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png","contentUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png","width":1276,"height":596,"caption":"Osmosis Blog"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158","name":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g","caption":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE"},"description":"Author\/Reviewer Paige Randall, PhD, MS, RN, CEN, CNE, has been a Registered Nurse for more than a decade and has a clinical background in cardiac, emergency nursing, and nursing education Elizabeth Lucas, EdD, RN, CNE, has been a Registered Nurse since 2008 with a clinical background in oncology working in a Medical Oncology Unit, a Critical Care Bone Marrow Transplant Unit, and a Hematology\/Oncology Clinic.","url":"https:\/\/www.osmosis.org\/blog\/author\/paigeandlizqotd"}]}},"jetpack_featured_media_url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/08\/NCLEX-LPN-Question-of-the-day-leukemic-blast-cells.jpg","jetpack-related-posts":[{"id":7283,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-anemia-risk","url_meta":{"origin":7314,"position":0},"title":"NCLEX-LPN\u00ae Question of the Day: Anemia risk","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"July 28, 2025","format":false,"excerpt":"Challenge your LPN nursing knowledge by identifying key risk factors for anemia in a patient with fatigue and a mechanical heart valve. Which factor increases anemia risk?","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX LPN Question of the day anemia risk","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/07\/NCLEX-LPN-Question-of-the-day-anemia-risk.jpg","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/07\/NCLEX-LPN-Question-of-the-day-anemia-risk.jpg 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/07\/NCLEX-LPN-Question-of-the-day-anemia-risk.jpg 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/07\/NCLEX-LPN-Question-of-the-day-anemia-risk.jpg 2x"},"classes":[]},{"id":9272,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-thalassemia","url_meta":{"origin":7314,"position":1},"title":"NCLEX-LPN\u00ae Question of the Day: Thalassemia","author":"Amber J. Dortch, FNP &amp; Mary Roberts, BSN, MSN","date":"February 16, 2026","format":false,"excerpt":"Understand the genetic and clinical aspects of thalassemia to effectively educate patients about this blood disorder and its impact on health.","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX\u00ae LPN Question of the Day: Thalassemia","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/02\/NCLEX-LPN-Question-of-the-Day-Thalassemia-1075.png","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/02\/NCLEX-LPN-Question-of-the-Day-Thalassemia-1075.png 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/02\/NCLEX-LPN-Question-of-the-Day-Thalassemia-1075.png 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/02\/NCLEX-LPN-Question-of-the-Day-Thalassemia-1075.png 2x"},"classes":[]},{"id":8094,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-blood-brain-barrier","url_meta":{"origin":7314,"position":2},"title":"NCLEX-LPN\u00ae Question of the Day: Blood brain barrier","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"October 8, 2025","format":false,"excerpt":"Explore the components and role of the blood-brain barrier in maintaining brain health and protecting the central nervous system.","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX LPN Question of the Day blood brain barrier","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/10\/NCLEX-LPN-Question-of-the-Day-blood-brain-barrier.jpg","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/10\/NCLEX-LPN-Question-of-the-Day-blood-brain-barrier.jpg 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/10\/NCLEX-LPN-Question-of-the-Day-blood-brain-barrier.jpg 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/10\/NCLEX-LPN-Question-of-the-Day-blood-brain-barrier.jpg 2x"},"classes":[]},{"id":9803,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-type-ii-diabetes-mellitus","url_meta":{"origin":7314,"position":3},"title":"NCLEX\u00ae LPN Question of the Day: Type II diabetes mellitus","author":"Donna Bacchus, PhD, RN","date":"April 13, 2026","format":false,"excerpt":"When risk factors for type 2 diabetes crop up in an EHR, a practical approach matters. Find out how nurses structure a patient history, apply key risk indicators, and design preventive strategies to help patients reduce risk and improve outcomes in today's NCLEX LPN question of the day.","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX\u00ae LPN Question of the Day Type II Diabetes","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/04\/NCLEX-LPN-Question-of-the-Day-Type-II-Diabetes.jpg","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/04\/NCLEX-LPN-Question-of-the-Day-Type-II-Diabetes.jpg 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/04\/NCLEX-LPN-Question-of-the-Day-Type-II-Diabetes.jpg 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2026\/04\/NCLEX-LPN-Question-of-the-Day-Type-II-Diabetes.jpg 2x"},"classes":[]},{"id":3285,"url":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-dka","url_meta":{"origin":7314,"position":4},"title":"NCLEX-RN\u00ae Question of the Day: Diabetic ketoacidosis (DKA)","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"April 17, 2024","format":false,"excerpt":"Discover nursing priorities for a child with DKA and signs of altered breathing. Learn to assess leukemia outcomes based on infection control measures. This NCLEX question of the day covers the topic and provides essential information for nursing students and professionals. The nurse in the intensive care unit is caring\u2026","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX\u00ae QOTD: DKA","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T101331.308.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T101331.308.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T101331.308.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T101331.308.webp 2x"},"classes":[]},{"id":875,"url":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome","url_meta":{"origin":7314,"position":5},"title":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"February 1, 2023","format":false,"excerpt":"Today's NCLEX-RN\u00ae question of the day focuses on a nurse caring for a group of clients in the oncology unit. Which client is most likely to develop tumor lysis syndrome (TLS)?\u00a0Can you figure it out? The nurse is caring for a group of clients on the oncology unit. Which client\u2026","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp 2x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/7314","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/users\/279"}],"replies":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/comments?post=7314"}],"version-history":[{"count":6,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/7314\/revisions"}],"predecessor-version":[{"id":7544,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/7314\/revisions\/7544"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media\/7316"}],"wp:attachment":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media?parent=7314"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/categories?post=7314"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/tags?post=7314"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}