{"id":875,"date":"2023-02-01T16:51:00","date_gmt":"2023-02-01T16:51:00","guid":{"rendered":"https:\/\/www.osmosis.org\/blog\/?p=875"},"modified":"2026-03-20T13:51:47","modified_gmt":"2026-03-20T21:51:47","slug":"nclex-qotd-tumor-lysis-syndrome","status":"publish","type":"post","link":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome","title":{"rendered":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_80 ez-toc-wrap-center counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">In This Article<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\/#The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\" >The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\/#A_An_82-year-old_client_diagnosed_with_acute_leukemia_receiving_chemotherapy\" >A. An 82-year-old client diagnosed with acute leukemia receiving chemotherapy<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\/#Major_Takeaway\" >Major Takeaway<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\/#Incorrect_answer_explanations\" >Incorrect answer explanations<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\/#B_A_34-year-old_client_in_remission_for_6-months_for_breast_cancer\" >B. A 34-year-old client in remission for 6-months for breast cancer<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\/#C_An_8-year-old_client_newly_diagnosed_with_stage_I_bone_cancer\" >C. An 8-year-old client newly diagnosed with stage I bone cancer&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\/#D_A_42-year-old_client_with_a_history_of_alcohol_abuse_diagnosed_with_melanoma\" >D. A 42-year-old client with a history of alcohol abuse diagnosed with melanoma<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n<p class=\"wp-block-paragraph\"><strong><em>Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a nurse caring for a group of clients in the oncology unit. Which client is most likely to develop tumor lysis syndrome (TLS)?<\/em><em>&nbsp;Can you figure it out?<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The nurse is caring for a group of clients on the oncology unit. Which client is most likely to develop tumor lysis syndrome (TLS)?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A. An 82-year-old client diagnosed with acute leukemia receiving chemotherapy<\/strong><strong>B. A 34-year-old client in remission for 6-months for breast cancer<br><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C. An 8-year-old client newly diagnosed with stage I bone cancer&nbsp;<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>D. A 42-year-old client with a history of alcohol abuse diagnosed with melanoma<\/strong>Scroll down for the correct answer!<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"The_correct_answer_to_todays_NCLEX-RN%C2%AE_Question_is%E2%80%A6\"><\/span>The correct answer to today&#8217;s NCLEX-RN\u00ae Question is&#8230;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"A_An_82-year-old_client_diagnosed_with_acute_leukemia_receiving_chemotherapy\"><\/span>A. An 82-year-old client diagnosed with acute leukemia receiving chemotherapy<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:&nbsp;<\/strong>TLS is most often caused by chemotherapeutic treatment of hematological malignancies, such as leukemia. A diagnosis of leukemia paired with older age puts this client at the highest risk.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Major_Takeaway\"><\/span>Major Takeaway<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Tumor Lysis Syndrome (TLS) is caused by a complication during treatment of hematological malignancies, such as leukemia and lymphoma, when chemotherapeutic medications rapidly kill large numbers of tumor cells at once. There are some factors that may put clients at risk of TLS, such as older age and having a large tumor burden, which can be evidenced by the presence of a very high white blood cell count and high lactate dehydrogenase (LDH), as well as bone marrow involvement by the malignancy. Finally, the risk of TLS is also higher with the use of substances that increase the uric acid levels in blood, such as alcohol and medications like thiazide diuretics or levodopa.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Incorrect_answer_explanations\"><\/span>Incorrect answer explanations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"B_A_34-year-old_client_in_remission_for_6-months_for_breast_cancer\"><\/span>B. A 34-year-old client in remission for 6-months for breast cancer<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong>&nbsp;This client is in remission and is not at the highest risk for TLS compared to another client.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"C_An_8-year-old_client_newly_diagnosed_with_stage_I_bone_cancer\"><\/span>C. An 8-year-old client newly diagnosed with stage I bone cancer&nbsp;<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:&nbsp;<\/strong>Although risk for TLS increases as bone marrow involvement by the malignancy occurs, this client is not at the highest risk for TLS compared to another client.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"D_A_42-year-old_client_with_a_history_of_alcohol_abuse_diagnosed_with_melanoma\"><\/span>D. A 42-year-old client with a history of alcohol abuse diagnosed with melanoma<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Rationale:<\/strong>\u00a0Although alcohol abuse does increase the risk of developing TLS, there is another client who is at a higher risk of developing TLS. TLS is not commonly associated with melanoma.<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><strong><em>________________________<\/em><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><strong><em>Want more NCLEX\u00ae-style practice questions? Try Osmosis today! Access your&nbsp;<a href=\"https:\/\/www.osmosis.org\/login?type=create\" target=\"_blank\" rel=\"noreferrer noopener\">free trial<\/a>&nbsp;and find out why millions of current and future clinicians and caregivers love learning with us.<\/em><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.osmosis.org\/plans\/rn\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"498\" height=\"178\" src=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/08\/42.png?w=498\" alt=\"\" class=\"wp-image-439\" srcset=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/08\/42.png 498w, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/08\/42.png?resize=300,107 300w\" sizes=\"auto, (max-width: 498px) 100vw, 498px\" \/><\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a nurse caring for a group of clients in the oncology unit. Which client is most likely to develop tumor lysis syndrome (TLS)?&nbsp;Can you figure it out? The nurse is caring for a group of clients on the oncology unit. Which client is most likely to develop [&hellip;]<\/p>\n","protected":false},"author":279,"featured_media":876,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[20,29,1367,32],"tags":[],"class_list":["post-875","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-exam-prep","category-nclex","category-nclex-rn","category-nursing"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog\" \/>\n<meta property=\"og:description\" content=\"Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a nurse caring for a group of clients in the oncology unit. Which client is most likely to develop tumor lysis syndrome (TLS)?&nbsp;Can you figure it out? The nurse is caring for a group of clients on the oncology unit. Which client is most likely to develop [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\" \/>\n<meta property=\"og:site_name\" content=\"Osmosis Blog\" \/>\n<meta property=\"article:published_time\" content=\"2023-02-01T16:51:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-20T21:51:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1081\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":[\"Article\",\"BlogPosting\"],\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\"},\"author\":{\"name\":\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158\"},\"headline\":\"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)\",\"datePublished\":\"2023-02-01T16:51:00+00:00\",\"dateModified\":\"2026-03-20T21:51:47+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\"},\"wordCount\":439,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp\",\"articleSection\":[\"Exam Prep\",\"NCLEX\",\"NCLEX-RN\",\"Registered Nursing (RN)\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\",\"url\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\",\"name\":\"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog\",\"isPartOf\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp\",\"datePublished\":\"2023-02-01T16:51:00+00:00\",\"dateModified\":\"2026-03-20T21:51:47+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage\",\"url\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp\",\"contentUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp\",\"width\":1081,\"height\":1080},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.osmosis.org\/blog\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#website\",\"url\":\"https:\/\/www.osmosis.org\/blog\/\",\"name\":\"Osmosis Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.osmosis.org\/blog\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#organization\",\"name\":\"Osmosis Blog\",\"url\":\"https:\/\/www.osmosis.org\/blog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png\",\"contentUrl\":\"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png\",\"width\":1276,\"height\":596,\"caption\":\"Osmosis Blog\"},\"image\":{\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158\",\"name\":\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g\",\"caption\":\"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE\"},\"description\":\"Author\/Reviewer Paige Randall, PhD, MS, RN, CEN, CNE, has been a Registered Nurse for more than a decade and has a clinical background in cardiac, emergency nursing, and nursing education Elizabeth Lucas, EdD, RN, CNE, has been a Registered Nurse since 2008 with a clinical background in oncology working in a Medical Oncology Unit, a Critical Care Bone Marrow Transplant Unit, and a Hematology\/Oncology Clinic.\",\"url\":\"https:\/\/www.osmosis.org\/blog\/author\/paigeandlizqotd\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome","og_locale":"en_US","og_type":"article","og_title":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog","og_description":"Today&#8217;s NCLEX-RN\u00ae question of the day focuses on a nurse caring for a group of clients in the oncology unit. Which client is most likely to develop tumor lysis syndrome (TLS)?&nbsp;Can you figure it out? The nurse is caring for a group of clients on the oncology unit. Which client is most likely to develop [&hellip;]","og_url":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome","og_site_name":"Osmosis Blog","article_published_time":"2023-02-01T16:51:00+00:00","article_modified_time":"2026-03-20T21:51:47+00:00","og_image":[{"width":1081,"height":1080,"url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp","type":"image\/webp"}],"author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":["Article","BlogPosting"],"@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#article","isPartOf":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome"},"author":{"name":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158"},"headline":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)","datePublished":"2023-02-01T16:51:00+00:00","dateModified":"2026-03-20T21:51:47+00:00","mainEntityOfPage":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome"},"wordCount":439,"commentCount":0,"publisher":{"@id":"https:\/\/www.osmosis.org\/blog\/#organization"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage"},"thumbnailUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp","articleSection":["Exam Prep","NCLEX","NCLEX-RN","Registered Nursing (RN)"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome","url":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome","name":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS) - Osmosis Blog","isPartOf":{"@id":"https:\/\/www.osmosis.org\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage"},"thumbnailUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp","datePublished":"2023-02-01T16:51:00+00:00","dateModified":"2026-03-20T21:51:47+00:00","breadcrumb":{"@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#primaryimage","url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp","contentUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp","width":1081,"height":1080},{"@type":"BreadcrumbList","@id":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-lysis-syndrome#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.osmosis.org\/blog"},{"@type":"ListItem","position":2,"name":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)"}]},{"@type":"WebSite","@id":"https:\/\/www.osmosis.org\/blog\/#website","url":"https:\/\/www.osmosis.org\/blog\/","name":"Osmosis Blog","description":"","publisher":{"@id":"https:\/\/www.osmosis.org\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.osmosis.org\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.osmosis.org\/blog\/#organization","name":"Osmosis Blog","url":"https:\/\/www.osmosis.org\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png","contentUrl":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/07\/OsmosisElsevierStacked.png","width":1276,"height":596,"caption":"Osmosis Blog"},"image":{"@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/131a18b6ecda9e9a8aac2894efb9d158","name":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.osmosis.org\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/d6c2ca8e1c8eafcaf906ff92af24958d629f6c8203487bb2f1a5aebceb746a9e?s=96&d=mm&r=g","caption":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE"},"description":"Author\/Reviewer Paige Randall, PhD, MS, RN, CEN, CNE, has been a Registered Nurse for more than a decade and has a clinical background in cardiac, emergency nursing, and nursing education Elizabeth Lucas, EdD, RN, CNE, has been a Registered Nurse since 2008 with a clinical background in oncology working in a Medical Oncology Unit, a Critical Care Bone Marrow Transplant Unit, and a Hematology\/Oncology Clinic.","url":"https:\/\/www.osmosis.org\/blog\/author\/paigeandlizqotd"}]}},"jetpack_featured_media_url":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/tumor-lysis-syndrome.webp","jetpack-related-posts":[{"id":1463,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-tumor-lysis-syndrome","url_meta":{"origin":875,"position":0},"title":"NCLEX-RN\u00ae Question of the Day: Tumor lysis syndrome (TLS)","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"March 16, 2022","format":false,"excerpt":"Today's NCLEX-RN\u00ae question of the day focuses on a nurse reviewing laboratory results on an oncology unit.\u00a0 The nurse is reviewing the blood work drawn for a client on the oncology unit. The nurse should recognize which laboratory result correlates with a diagnosis of tumor lysis syndrome (TLS)? A. Phosphorus\u2026","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX\u00ae Question of the Day: Tumor Lysis Syndrome","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/50.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/50.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/50.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/50.webp 2x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/50.webp 3x"},"classes":[]},{"id":1306,"url":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-tumor-in-sigmoid-colon","url_meta":{"origin":875,"position":1},"title":"NCLEX-RN\u00ae Question of the Day: Tumor in sigmoid colon","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"April 12, 2023","format":false,"excerpt":"Today's NCLEX-RN\u00ae question of the day focuses on a client that is diagnosed with a malignant tumor of the sigmoid colon. Which type of cancer does this client most likely have?\u00a0Can you figure it out? The nurse is caring for a client recently diagnosed with a malignant tumor of the\u2026","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2023\/04\/nclex-tumor-sigmoid-colon.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2023\/04\/nclex-tumor-sigmoid-colon.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2023\/04\/nclex-tumor-sigmoid-colon.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2023\/04\/nclex-tumor-sigmoid-colon.webp 2x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2023\/04\/nclex-tumor-sigmoid-colon.webp 3x"},"classes":[]},{"id":5061,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-diaphragmatic-hernia","url_meta":{"origin":875,"position":2},"title":"NCLEX-RN\u00ae Question of the Day: Diaphragmatic hernia","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"February 12, 2025","format":false,"excerpt":"The nurse in the neonatal intensive care unit (NICU) is caring for a client diagnosed with congenital diaphragmatic hernia. The nurse should anticipate which other diagnosis for this client?","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX Question of the day Diaphragmatic hernia","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/NCLEX_QotD_Q1_Diaphragmatic_hernia_2025_SM.png","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/NCLEX_QotD_Q1_Diaphragmatic_hernia_2025_SM.png 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/NCLEX_QotD_Q1_Diaphragmatic_hernia_2025_SM.png 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/NCLEX_QotD_Q1_Diaphragmatic_hernia_2025_SM.png 2x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2025\/01\/NCLEX_QotD_Q1_Diaphragmatic_hernia_2025_SM.png 3x"},"classes":[]},{"id":3274,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-vaginal-candidiasis-infection-tasks-for-an-assistive-personnel","url_meta":{"origin":875,"position":3},"title":"NCLEX-RN\u00ae Question of the Day: Vaginal candidiasis infection tasks for assistive personnel","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"October 26, 2022","format":false,"excerpt":"Today's NCLEX-RN\u00ae question of the day focuses on a nurse who is delegating a task to the assistive personnel regarding a client with vaginal candidiasis infection. Can you figure it out? A client with a diagnosis of acquired immunodeficiency syndrome (AIDS) has recently developed a vaginal candidiasis infection. Which task\u2026","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"NCLEX\u00ae Question of the Day: Vaginal Candidiasis Infection Tasks for an Assistive Personnel","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T095851.337.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T095851.337.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T095851.337.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T095851.337.webp 2x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/2024-09-18T095851.337.webp 3x"},"classes":[]},{"id":987,"url":"https:\/\/www.osmosis.org\/blog\/nclex-qotd-guillain-barre-syndrome-gbs","url_meta":{"origin":875,"position":4},"title":"NCLEX-RN\u00ae Question of the Day: Guillain-Barr\u00e9 syndrome (GBS)","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"August 16, 2023","format":false,"excerpt":"Prepare for the NCLEX-RN\u00ae\u00a0with this focused topic on Guillain-Barr\u00e9 syndrome (GBS) and medication classification. Learn about the nurse's role in caring for a client with GBS after a severe viral infection. Discover the essential medications the health care provider may prescribe to manage this condition effectively. Ideal for nursing students\u2026","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-guillain-barre-syndrome.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-guillain-barre-syndrome.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-guillain-barre-syndrome.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-guillain-barre-syndrome.webp 2x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-guillain-barre-syndrome.webp 3x"},"classes":[]},{"id":1232,"url":"https:\/\/www.osmosis.org\/blog\/nclex-question-of-the-day-agitated-dementia-client","url_meta":{"origin":875,"position":5},"title":"NCLEX-RN\u00ae Question of the Day: Agitated dementia client","author":"Paige Randall, PhD, MS, RN, CNE &amp; Elizabeth Lucas, EdD, RN, CNE","date":"March 2, 2022","format":false,"excerpt":"Today's NCLEX-RN\u00ae question of the day focuses on how a nurse should handle an agitated client diagnosed with dementia. The nurse in the medical-surgical unit is caring for a client diagnosed with dementia. The client becomes agitated and starts to yell at the nurse and other hospital staff. Which is\u2026","rel":"","context":"In &quot;Exam Prep&quot;","block_context":{"text":"Exam Prep","link":"https:\/\/www.osmosis.org\/blog\/category\/exam-prep"},"img":{"alt_text":"","src":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-agitated-dementia-client.webp","width":350,"height":200,"srcset":"https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-agitated-dementia-client.webp 1x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-agitated-dementia-client.webp 1.5x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-agitated-dementia-client.webp 2x, https:\/\/www.osmosis.org\/blog\/wp-content\/uploads\/sites\/2\/2024\/09\/nclex-agitated-dementia-client.webp 3x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/875","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/users\/279"}],"replies":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/comments?post=875"}],"version-history":[{"count":5,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/875\/revisions"}],"predecessor-version":[{"id":7072,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/posts\/875\/revisions\/7072"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media\/876"}],"wp:attachment":[{"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/media?parent=875"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/categories?post=875"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.osmosis.org\/blog\/wp-json\/wp\/v2\/tags?post=875"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}