Alzheimer disease Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 60-year-old man is brought to the primary care clinic by his partner due to concern for Alzheimer disease. The patient has become increasingly forgetful and has difficulty with everyday tasks, like managing finances and following recipes. The patient recently got lost in a familiar place and appears to have lost interest in gardening and participating in the neighborhood gardening club. Past medical history includes hypertension managed with lisinoprilThe patient has no history of substance use or smokingTemperature is 37.0°C (98.6°F), pulse is 80/min, respirations are 12/min, and blood pressure is 132/85 mmHg. His affect is flat. Mini-Mental State Examination (MMSE) score is 23/30 and a depression screening tool suggests minimal symptoms. Physical examination reveals that stroking the palmar muscles at the base of the thumb elicits contraction of the mentalis muscle, and placing the physician’s finger in the patient’s palm elicits a grasp reflex. Brain magnetic resonance imaging (MRI) demonstrates marked atrophy of the frontal lobes and anterior temporal regions with relative preservation of parietal and occipital cortices. Which of the following diagnostic features argues against this diagnosis 

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