Apnea, hypoventilation and pulmonary hypertension Quiz: Ace Your Exams
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A 56-year-old man presents to his family physician for a routine checkup. Upon walking the short distance from the waiting room to the exam room, the patient becomes short of breath. He states that he frequently feels tired throughout the day and has had these symptoms for years. His previous physician performed a full cardiac workup, which was unremarkable. Temperature is 99.0°F, blood pressure is 150/110 mm Hg, pulse is 90/min, respirations are 25/min and oxygen saturation is 94% on room air. The patient has a BMI of 42 kg/m2. The patient undergoes in-laboratory polysomnography testing, which demonstrates hypoventilation during sleep. Further laboratory testing demonstrates an elevated serum bicarbonate level. Which of the following best describes the underlying pathophysiology of this patient’s clinical condition?
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