Approach to jaundice (unconjugated hyperbilirubinemia) Quiz: Ace Your Exams
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A 48-year-old man presents to the primary care clinic due to new yellowing of the skin. This has been gradually worsening for the past week. The patient has never experienced this before. Past medical history is significant for HIV, hypertension, and active tuberculosis. Current medications include bictegravir-emtricitabine-tenofovir, losartan, rifampin, isoniazid, pyrazinamide, and ethambutol. Vital signs are unremarkable. On physical examination, the patient is noticeably jaundiced. Bloodwork is drawn in the office and the results are shown below. Which of the following is the most likely diagnosis?
| Serum Test | Result |
| Haptoglobin | Increased |
| LDH | 190 U/L (nml: 140-280 U/L) |
| Total Bilirubin | 6.0 mg/dL |
| Direct Bilirubin | 0.5 mg/dL |
| AST | 19 U/L |
| ALT | 15 U/L |
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