Approach to lymphoma Quiz: Ace Your Exams
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A 25-year-old woman presents to the clinic with a two-month history of painless swelling in her neck and recent onset of night sweats, fevers, fatigue, and unintentional weight loss of 5 kg (11 lbs.). She has not had any recent infections, and she has no significant past medical history. Physical examination reveals a firm, non-tender, 4 cm lymph node in the right cervical region and a palpable 3 cm lymph node in the left axilla. Cardiopulmonary and abdominal exams are within normal limits. Laboratory results are shown below. Lymph node biopsy is performed and reveals large, binucleated cells with prominent "owl's eye" nucleoli. Which of the following is the best next step in management?
| Lab Test | Result |
| Hemoglobin | 10.5 g/dL |
| Leukocyte count | 4,800/mm³ |
| Platelet count | 210,000/mm³ |
| Lactate dehydrogenase (LDH) | 350 U/L |
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