Approach to pneumoperitoneum and peritonitis (perforated viscus) Quiz: Ace Your Exams

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A 47-year-old man presents to the emergency department for evaluation of abdominal pain, nausea, and vomiting for the past four days. The patient lives alone and was discovered by a family member today covered in vomitus. The patient drinks alcohol daily and does not have other known medical problems.  Temperature is 39 ºC (102.2 ºF), pulse is 101/min, blood pressure is 100/77 mmHg and respirations are 18/min. The patient has evidence of scleral icterus and appears jaundiced. Physical examination demonstrates a distended abdomen, with evidence of rebound pain and guarding, as well as a positive fluid wave. Abdominal radiograph is within normal limits and initial blood work is shown below. A CT of the abdomen and pelvis demonstrates evidence of large intra abdominal ascites and cirrhotic liver morphology. Which of the following is the most likely cause of this patient's presentation?

Laboratory value
Result
Complete Blood Count (CBC)
Hemoglobin
9.8 g/dL
White blood cell count (WBC)
27,000/mm3
Liver Function Tests
Alkaline phosphatase (ALP)
300 u/L
Alanine aminotransferase (ALT)
238 u/L
Aspartate aminotransferase (AST)
159 u/L
Total bilirubin
6 mg/dL
INR
1.8
Serum chemistry
Lipase
50 U/L

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