Approach to vasculitis Quiz: Ace Your Exams
Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!
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A 28-year-old man is evaluated in the emergency department for one week of progressive fatigue, cough and dyspnea, and hemoptysis that occurred today, causing him to call an ambulance. He has no significant medical history and takes no medication. He has smoked a pack per day for 8 years. He is unable to speak in full sentences, so additional history is limited. Temperature is 37 ºC (98.6 °F), heart rate is 130/min, blood pressure is 102/62 mmHg, respiratory rate is 34/min, and oxygen saturation is 84% on room air. The patient appears diaphoretic and pale. Accessory muscles are used during respiration. Auscultation of the lungs reveals crackles diffusely in the bilateral lung fields. Laboratory values are shown below. Chest X-ray reveals diffuse bilateral interstitial opacities. Which of the following is the best next step in management?
| Laboratory study | Result |
| Creatinine | 2.7 mg/dL |
| Antinuclear antibodies (ANA) | Negative |
| Anti-myeloperoxidase (anti-MPO) antibodies | Negative |
| Antiproteinase-3 antibodies | Negative |
| Anti-glomerular basement membrane (anti-GBM) antibodies | Positive |
| Urinalysis | 3+ blood 3+ protein Numerous erythrocytes and erythrocyte casts |
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