Disseminated intravascular coagulation Quiz: Ace Your Exams
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A 58-year-old man with a history of alcohol use disorder is admitted to the intensive care unit with a diagnosis of acute pancreatitis. On the third day of hospitalization, he has several episodes of hematemesis. Temperature is 38.2°C (100.8°F), blood pressure is 85/50 mm Hg, heart rate is 124 /minute, respiratory rate is 20 /minute, and oxygen saturation is 95% on 2 L via nasal cannula. Physical examination reveals diffuse abdominal tenderness without rebound or guarding. Bleeding is noted at his peripheral IV sites. A comparison of laboratory results from this hospitalization is shown in the table below. Which of the following is the most appropriate next step in management?
| Laboratory Test | Admission Result | Day 3 Result |
| Hemoglobin | 11.1 g/dL | 7.5 g/dL |
| Platelet count | 200,000 /µL | 45,000 /µL |
| Prothrombin time (PT) | 12 seconds | 22 seconds |
| Partial thromboplastin time (aPTT) | 30 seconds | 60 seconds |
| Fibrinogen | N/A | 120 mg/dL |
| D-dimer | N/A | 5 µg/mL |
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