Drug misuse, intoxication and withdrawal Quiz: Ace Your Exams

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A 2-day-old female neonate is examined in the newborn nursery to evaluate poor feeding. The infant was born vaginally to a 28-year-old woman who did not receive consistent prenatal care during her pregnancy. The pregnancy was complicated by intrauterine growth restriction. The infant was breastfed normally until two hours ago when she became tachypneic and restless. Temperature is 37.8°C (100°F), pulse is 170/min, respirations are 85/min, and blood pressure is 60/35 mmHg. Physical examination shows increased tone in all extremities. The patient appears diaphoretic and has a high-pitched cry and occasional sneezes. There are no dysmorphic facial features. Which of the following best describes the underlying etiology of this infant’s presentation?

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Nondisjunction resulting in an extra copy of chromosome 21

In utero exposure to rubella

In utero exposure to opiates

In utero exposure to alcohol

Fragile X mental retardation one gene mutation