Early pregnancy loss Quiz: Ace Your Exams
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A 32-year-old woman, gravida 4, para 3, at 10 weeks of gestational age presents to the emergency department at noon with heavy vaginal bleeding and severe pelvic pain. This morning, she soaked through four pads in an hour and passed multiple large clots, some of which appeared to contain tissue—though she has been using the same pad for the past two hours. The pain is currently rated a 5 on a 10-point scale, though at its peak, it was a 9 and radiated to her lower back and thighs. An ultrasound performed two weeks ago showed a viable fetus with cardiac activity. The medical history is notable for three prior uncomplicated vaginal deliveries. Temperature is 36.6°C (97.9°F), pulse is 76/min, respirations are 16/min, and blood pressure is 122/78 mmHg. On exam, the cervical os is closed and several small blood clots are visible in the vagina. Lab results are shown below. An ultrasound shows a thickened endometrial lining without an intrauterine fluid collection; the adnexa appear grossly normal. IV fluids and analgesics are administered. What is the most appropriate next step in management?
| Laboratory test | Result | Reference range |
| Blood type | A-negative | Not applicable |
| Hemoglobin | 10.8 g/dL | 12-16 g/dL |
| Platelets | 304,000/mm3 | 150,000-400,000/mm3 |
| Prothrombin time | 12 sec | 11-15 sec |
| Activated partial thromboplastin time | 30 sec | 25-40 sec |
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