Renal failure Quiz: Ace Your Exams

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A 48-year-old woman presents to the emergency department for evaluation of intractable vomiting for the past 24 hours. Last night she ate a hamburger from a local restaurant, and since then she has had multiple episodes of bilious emesis. Past medical history is significant for osteoarthritis and hypertension. Current medications include ibuprofen and lisinopril. Her temperature is 36.6°C (97.8° F), pulse is 110/min, respirations are 21/min, and blood pressure is 101/62 mm Hg. Physical examination demonstrates decreased skin turgor and dry oral mucosa. A liver function assay is within normal limits. The remainder of the laboratory studies are shown below.  

 Laboratory value  Result 
 Complete blood count 
 Hemoglobin  13 g/dL 
 Leukocytes  10,000 /mL 
 Platelets  330,000/mm3 
 Serum chemistry 
 Sodium  136 mEq/L 
 Potassium  2.8 mEq/L 
 Chloride  85 mEq/L 
 Bicarbonate  29 mEq/L 
 Creatinine  1.7 mg/dL 
 Blood urea nitrogen (BUN)  40 mg/dL 
 Urinalysis 
 Erythrocytes  1-2/hpf 
 Leukocytes  1-2/hpf 
 Fractional excretion of sodium (FENa <1% 
 Urine osmolality  650 mOsm/kg 
 Sediment  None 
   
Which of the following is the most likely etiology of this patient's clinical condition? 

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