Lobular carcinoma in situ Quiz: Ace Your Exams

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A 42-year-old woman presents for follow-up of a core biopsy done for microcalcifications seen on screening mammography. Past medical history is significant for hypertension for which she takes hydrochlorothiazide. Temperature is 36.9 °C (98.42°F), heart rate is 72 bpm, respirations are 14/min, and blood pressure is 139/96 mmHg.  The biopsy report shows no evidence of invasive ductal or lobular carcinoma. However, lobular carcinoma in situ (LCIS) is noted with small cell proliferation with distinctive cell borders and small, uniform round-to-oval nuclei. After a thorough risk assessment, the management plan calls for close follow-up with an increased frequency of breast exams and breast imaging. Based on the pathology findings and the management strategy, which of the following was most likely diagnosed?

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