Renal failure Quiz: Ace Your Exams

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A 65-year-old man comes to the emergency department for evaluation of lower abdominal discomfort for an hour. He has not urinated since yesterday and has had difficulty initiating urination for the past three months. He has not had weight loss, dysuria, urgency, or dribbling of urine. The patient had a viral illness two days ago for which he started taking acetaminophen for fever. Current vitals are within normal limits. Physical examination demonstrates a palpable mass in the suprapubic area. A symmetric, enlarged non-tender prostate is palpated on digital rectal examination. Glomerular filtration rate is 40 mL/min/1.73m2  (reference range: 90-120 mL/min/1.73m2). Urinalysis is shown.

 Laboratory value  Result  Reference range 
 Serum chemistry  
 Blood urea nitrogen  36 mg/dL  7-18 mg/dL 
 Creatinine  1.9 mg/dL  0.6-1.2 mg/dL 
 Urinalysis  
 Proteinuria  None  None 
 Dysmorphic red blood cells  None  None 
 Sodium (UNa 15 mEq/L  20 mEq/L 
 Fractional excretion of sodium (FENa <1%  1-2% 
 Urine osmolality  650 mOsm/kg  50-1,400 mOsm/kg 
 Sediment  None  None 


If left untreated, which of the following laboratory findings are most likely to be observed in the coming weeks?

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