AssessmentsAbdominal pain: Clinical practice
USMLE® Step 1 style questions USMLE
USMLE® Step 2 style questions USMLE
A 27-year-old man presents to his primary care doctor’s office after he felt a right testicular mass a week ago. He notes he has had a dull, intermittent ache in his groin for the past 2 months, which has had attributed to strenuous exercises as a personal trainer. His past medical history is significant for surgical correction of right-sided cryptorchidism at the age of 1. On physical examination, the patient’s right testicle is non-tender, but a firm and fixed mass is palpated. Transillumination is negative. An ultrasound of the right testicle demonstrates a heterogenous mass. Which of the following is the most appropriate next step?
Content Reviewers:Rishi Desai, MD, MPH
Abdominal pain is a very common complaint, and the differential diagnosis is wide, ranging from benign to life-threatening conditions.
Life-threatening conditions include a ruptured abdominal aortic aneurysm, mesenteric ischemia, perforation anywhere along the gastrointestinal tract, acute bowel obstruction, acute pancreatitis, peritonitis, ectopic pregnancy, ovarian torsion, and myocardial infarction.
There are three main types of abdominal pain: visceral, parietal, and referred pain.
Visceral pain happens when the nerves that run through the walls of an organ get stretched. The pain isn't usually well localized and feels like a dull ache or cramp.
Hollow organs cause an intermittent colicky type of pain, whereas solid organs cause a more constant pain.
Parietal pain is sharp and can be localized by pointing to a specific spot.
Finally, there’s referred pain which is when the brain mistakenly identifies pain as coming from one region like the shoulder when it’s actually coming from a different region like the diaphragm.
Abdominal pain, can often be separated into the abdominal area that’s involved.
Epigastric pain that’s associated with bloating, abdominal fullness, heartburn, or nausea is called dyspepsia, and it’s generally due to gastroesophageal reflux disease, gastritis, pancreatitis, or peptic ulcer disease - meaning an ulcer of the stomach or duodenum.
Acute pain with fever and an elevated white blood cell count suggests appendicitis.
There’s also mesenteric ischemia, which is when blood flow to the small intestines is interrupted, typically due to arterial or venous thromboembolism, and may cause severe pain and bloody stools, as well as progressive low blood pressure, rapid heart rate, and ultimately shock.
Some conditions cause diffuse abdominal pain that can’t be localized.
A surgical emergency is an abdominal aortic aneurysm that has ruptured. This can cause pain that radiates to the back, and a pulsating sensation in the abdomen.
The mnemonic OPQRST can be used to help with history taking - especially regarding pain. O stands for onset, whether it was acute, gradual, or an ongoing chronic problem.
P stands for provocation and palliation, so whether any movement, pressure, rest, or other factors make the pain better or worse.
Q stands for quality, whether the pain is sharp, dull, crushing, or burning. It also relates to the pattern, like intermittent, constant, or throbbing.
R stands for region and radiation, meaning the location, or where the pain is on the body, and whether it radiates or extends to any other areas.
S stands for severity, which can be quantified with a score on a scale of 0 to 10 - 0 being no pain and 10 being the worst possible pain.
And finally, T stands for time, so how long the condition has been going on and if it has changed over time.
Associated symptoms can also help narrow the diagnosis. Common ones are nausea, vomiting, constipation, diarrhea, and changes in stool like the presence of blood or mucus, a foul smell, or changes in stool caliber.
In females, it’s important to always rule out the possibility of pregnancy. Then, we should ask for genitourinary symptoms, such as dysuria, frequency, and hematuria - which can occur with a urinary tract infection or kidney stones.
Constitutional symptoms like fevers, chills, fatigue, and weight loss, would raise concern for an infection, malignancy, or systemic illness like inflammatory bowel disease.
To evaluate abdominal pain, the first step is inspection.
First, there’s the person’s general appearance and how they’re positioned given their pain. For example, if they’re perfectly still in bed with knees bent that’s concerning for peritonitis. Other features include how a person is breathing, signs of abdominal distention, and scars from past surgeries.
- "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
- "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
- "CURRENT Medical Diagnosis and Treatment 2020" McGraw-Hill Education / Medical (2019)
- "Robbins Basic Pathology" Elsevier (2017)
- "Diagnostic Immunohistochemistry" Elsevier (2021)
- "Bates' Guide to Physical Examination and History Taking" LWW (2016)
- "Atlas of Emergency Medicine" Wolters Kluwer (2015)
- "Chronic Abdominal Pain in General Practice" Digestive Diseases (2021)
- "Systematic review: interventions for abdominal pain management in inflammatory bowel disease" Alimentary Pharmacology & Therapeutics (2017)
- "Antispasmodics for Chronic Abdominal Pain: Analysis of North American Treatment Options" American Journal of Gastroenterology (2021)
- "A primary care approach to abdominal pain in adults" South African Family Practice (2021)
- "Chronic Abdominal Pain: Gastroenterologist Approach" Digestive Diseases (2021)