Acute tubular necrosis
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Flashcards
Acute tubular necrosis
0 of 17 complete
Questions
USMLE® Step 1 style questions USMLE
0 of 2 complete
Laboratory value | Result | ||
Urinalysis | |||
On admission | Day 2 | Day 8 | |
Creatinine | 1.1 mg/dL | 3.5 mg/dL | 2.3 mg/dL |
Memory Anchors and Partner Content
External References
First Aid
2024
2023
2022
2021
Acute tubular necrosis p. 620
Aminoglycosides p. 188
acute tubular necrosis p. 621
Cisplatin p. 445
acute tubular necrosis p. 621
Granular casts p. 612
acute tubular necrosis p. 621
Heart failure p. 316
acute tubular necrosis with p. 620
Hemoglobinuria
acute tubular necrosis and p. 621
Hemorrhage
acute tubular necrosis p. 621
Hypotension
acute tubular necrosis with p. 621
Ischemia p. 206, 685
acute tubular necrosis from p. 620
Lead poisoning p. 425, 430
acute tubular necrosis p. 620
Myoglobinuria
acute tubular necrosis p. 621
Sepsis
acute tubular necrosis p. 621
Shock p. 317
acute tubular necrosis p. 621
Tubular necrosis p. 612, 620, 620
Summary
Acute tubular necrosis (ATN) is a type of acute kidney injury (AKI) that results in the sudden and rapid death of tubular cells in the kidneys. This can lead to a decrease in urine production and an increase in the levels of creatinine and urea in the blood.
ATN may be caused by sepsis leading to hypotension and renal hypoperfusion; ischemia due to renal hypoperfusion, like in hypovolemic shock; but it can also be due to exposure to toxins and nephrotoxic drugs which cause damage to the tubular cells. Such drugs include nephrotoxic antibiotics, contrast agents used during imaging studies, amphotericin B, and toxic heavy metals.