Adrenal cortical carcinoma

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Adrenal cortical carcinoma

ETP Endocrine System

ETP Endocrine System

Pharyngeal arches, pouches, and clefts
Endocrine system anatomy and physiology
Anatomy of the thyroid and parathyroid glands
Anatomy of the abdominal viscera: Pancreas and spleen
Pituitary gland histology
Thyroid and parathyroid gland histology
Pancreas histology
Adrenal gland histology
Synthesis of adrenocortical hormones
Adrenocorticotropic hormone
Growth hormone and somatostatin
Hunger and satiety
Antidiuretic hormone
Thyroid hormones
Insulin
Insulins
Glucagon
Somatostatin
Cortisol
Testosterone
Estrogen and progesterone
Oxytocin and prolactin
Parathyroid hormone
Calcitonin
Vitamin D
Phosphate, calcium and magnesium homeostasis
Congenital adrenal hyperplasia
Adrenal insufficiency: Pathology review
Primary adrenal insufficiency
Waterhouse-Friderichsen syndrome
Hyperaldosteronism
Cushing syndrome and Cushing disease: Pathology review
Cushing syndrome
Conn syndrome
Pheochromocytoma
Adrenal masses: Pathology review
Adrenal masses and tumors: Clinical
Adrenal cortical carcinoma
Thyroglossal duct cyst
Hyperthyroidism
Hyperthyroidism: Pathology review
Graves disease
Thyroid eye disease (NORD)
Toxic multinodular goiter
Euthyroid sick syndrome
Hypothyroidism
Hypothyroidism: Pathology review
Hashimoto thyroiditis
Hypothyroidism and thyroiditis: Clinical
Subacute granulomatous thyroiditis
Riedel thyroiditis
Thyroid storm
Thyroid nodules and thyroid cancer: Pathology review
Thyroid cancer
Thyroid nodules and thyroid cancer: Clinical
Parathyroid disorders and calcium imbalance: Pathology review
Parathyroid conditions and calcium imbalance: Clinical
Hyperparathyroidism
Hypoparathyroidism
Hypercalcemia
Hypocalcemia
Diabetes mellitus
Diabetes mellitus: Pathology review
Diabetes mellitus: Clinical
Diabetic nephropathy
Diabetic retinopathy
Pancreatic neuroendocrine neoplasms
Diabetes insipidus and SIADH: Pathology review
Diabetes insipidus
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Hypopituitarism: Pathology review
Hypopituitarism
Hyperpituitarism
Pituitary adenoma
Pituitary apoplexy
Pituitary tumors: Pathology review
Sheehan syndrome
Hyperprolactinemia
Prolactinoma
Hypoprolactinemia
Gigantism
Acromegaly
Constitutional growth delay
Puberty and Tanner staging
Precocious puberty
Delayed puberty
Kallmann syndrome
Disorders of sex chromosomes: Pathology review
5-alpha-reductase deficiency
Menstrual cycle
Polycystic ovary syndrome
Premature ovarian failure
Menopause
Androgen insensitivity syndrome
Autoimmune polyglandular syndrome type 1 (NORD)
Multiple endocrine neoplasia: Pathology review
Multiple endocrine neoplasia
Carcinoid syndrome
Neuroblastoma
Opsoclonus myoclonus syndrome (NORD)
Hyperthyroidism medications
Hypothyroidism medications
Hypoglycemics: Insulin secretagogues
Miscellaneous hypoglycemics
Mineralocorticoids and mineralocorticoid antagonists
Adrenal hormone synthesis inhibitors

Assessments

Flashcards

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USMLE® Step 1 questions

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High Yield Notes

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Flashcards

Adrenal cortical carcinoma

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Questions

USMLE® Step 1 style questions USMLE

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A 44-year-old man comes to his physician complaining of muscle weakness and headaches for the past 2 months. He is a construction worker and has found it difficult to lift large objects during the job. The patient has no significant past medical history, but he states his blood pressure was “high” at a recent health fair. Temperature is 37.0°C (98.6°F), pulse is 82/min, and blood pressure is 165/92 mm Hg. Physical examination reveals no abnormalities. Laboratory testing reveals the following findings:

 
 Laboratory Value  Result 
 Serum 
 Sodium   147 mEq/L 
 Potassium   2.9 mEq/L 
 Chloride   105 mEq/L 
 HCO3-  32 mEq/L 
 Creatinine   0.6 mg/dL 
 Glucose  94 mg/dL 

Serum renin levels are decreased. Which of the following is the most likely cause of this patient’s condition?

Summary

Adrenal cortical carcinomas are rare tumors that arise from the outer layer of the adrenal gland called the adrenal cortex. They account for only about 1% of all cancers.

Adrenal cortical tumors can be either benign (noncancerous) or cancerous. The most common type of adrenal cortical tumor is a pheochromocytoma, arising from the chromaffin cell, which produces the hormone adrenaline.

Symptoms of an adrenal cortical carcinoma depend on the type but may include: feeling very tired, weight loss, truncal obesity, muscle weakness, and blood in the urine.