Assessment of Adrenal masses: Pathology review: Video & Anatomy | Osmosis

Question

A 15-month-old boy is brought to the clinic after his parents noticed frequent falls and abnormal twitching of his limbs over the past month. Prior to the onset of these symptoms, the patient had been walking without assistance and developing normally. Vital signs are within normal limits. Physical examination shows bilateral jerking eye movements and sporadic muscle contractions of the trunk and limbs. The patient has difficulty walking in a straight line and stumbles several times. A left-sided abdominal mass is palpated. Biopsy of the mass reveals small, round, blue cells arranged concentrically around a central neuropil. Staining with neuron-specific enolase is positive. Based on these findings, which of the following is most likely to be elevated? &#160;

Accepted Answer

Urinary vanillylmandelic acid

Answer

Aldosterone to renin ratio

Answer

24-hour urine cortisol

Answer

Urinary 5-hydroxyindoleacetic acid

Answer

Plasma phenylalanine

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Adrenal masses: Pathology review

Pathology

Endocrine system