Adrenoleukodystrophy (NORD)

A 24-year old man presents to his primary care physician’s clinic due to increasing weakness in his legs for the last three years. He notes that his legs feel very stiff. He reports that he had a maternal uncle with similar issues. On physical exam, the patient has decreased vibratory sensation in the bilateral lower extremities. He exhibits signs of early male pattern baldness. The physician confirms the suspected diagnosis via testing the patient’s plasma for accumulated very-long-chain fatty acids (VLCFA) and a mutation in the ABCD1 gene. Which of the following organelles is affected in this patient’s disease?