Osmosis: Amenorrhoea. (2019, May 23). Retrieved from (https://www.osmosis.org/learn/Amenorrhoea).
Amenorrhea is the absence of a menstrual period in a woman of reproductive age. Physiological states of amenorrhea are seen, most commonly, during pregnancy and lactation. Primary amenorrhea may be caused by developmental problems such as the congenital absence of the uterus, failure of the ovary to receive or maintain egg cells. Also, delay in pubertal development will lead to primary amenorrhoea. It is defined as an absence of menarche by 16 years of age. Workup should begin at age 13 if there is a complete absence of pubertal development. Secondary amenorrhea is often caused by hormonal disturbances from the hypothalamus and the pituitary gland, from premature menopause or intrauterine scar formation.