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Amyotrophic lateral sclerosis

Summary of Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a degenerative disorder of the corticospinal tract that involves the death of neurons. ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size. This results in difficulty speaking, swallowing, and eventually breathing. Most cases are sporadic however there can be a gene mutation in zinc-copper superoxide dismutase (SODl) which leads to free radical damage to neurons. 



Nervous system


Central nervous system disorders
Central and peripheral nervous system disorders
Peripheral nervous system disorders
Autonomic nervous system disorders
Nervous system pathology review

Amyotrophic lateral sclerosis


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High Yield Notes
6 pages

Amyotrophic lateral sclerosis

10 flashcards

USMLE® Step 1 style questions USMLE

9 questions

USMLE® Step 2 style questions USMLE

6 questions

A 55-year-old man comes to the clinic because of muscle weakness for the past two months. His temperature is 37.8°C (100°F), pulse is 72/min, respirations are 18/min, and blood pressure is 110/82 mm Hg. Physical examination shows wasting of the muscles in his hands and a positive Babinski sign. Which of the following is the most appropriate next step in management?

External References