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The gastrointestinal tract runs from the mouth all the way to the anus and contains the esophagus, the stomach, the small and large intestine and the anus. All these structures, like any other part of our body, are prone to injury or disease.
This video will give you a better understanding of the anatomy of the GI tract and how it relates to the clinical conditions that affect them!
Let’s start by looking at gastric and duodenal ulcers, which are open lesions in the lining of the stomach or duodenum that lead to inflammation in the gastric or duodenal wall.
These are often associated with a specific stomach bacteria called H. Pylori, H.Pylori....Helicobacter Pylori.
Duodenal ulcers are more frequent than gastric ulcers and can be located anywhere along the duodenal wall, classically affecting either the anterior or posterior duodenal wall. If severe enough, ulcers can erode through the duodenal wall, which can cause perforation or gastrointestinal bleeding.
Anterior wall duodenal ulcers are more prone to perforation into the anterior abdominal cavity, and this can result in a pneumoperitoneum, because air from the gastrointestinal tract enters the abdominal cavity.
A classic finding on x-ray is free air under the diaphragm indicating a pneumoperitoneum. This can also result in peritonitis, because as duodenal contents leak into the abdominal cavity, they irritate the peritoneum.
Posterior wall duodenal ulcers can also cause perforation, but more frequently, they cause upper gastrointestinal bleeding.
That’s because the first part of the duodenum, called the duodenal bulb, is positioned directly anterior to the gastroduodenal artery, so an erosion of the posterior wall can also cause erosion into the gastroduodenal artery resulting in an upper gastrointestinal bleed.
Most gastric ulcers are located at the lesser curvature of the stomach, an area where both the left and right gastric artery can be found perfusing the stomach.
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