Approach to dyspnea: Clinical sciences

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A 62-year-old man presents to the emergency department due to three days of shortness of breath and difficulty lying flat. The patient has not seen a physician in twenty years and takes no medications. The patient smokes one pack of cigarettes per day. Temperature is 37.4 ºC (99.3 ºF), pulse is 90/min, blood pressure is 136/84, respiratory rate is 20/min, and oxygen saturation (SpO2) is 90% on room air. Cardiac auscultation reveals normal S1 and S2. Pulmonary auscultation reveals rales at both lung bases and faint wheezes in bilateral mid-lung fields. There is mild non-pitting edema in both feet. Electrocardiogram shows normal sinus rhythm with voltage criteria of left ventricular hypertrophy. Serum electrolytes and kidney function are normal. Chest x-ray shows mild pulmonary congestion. Which of the following diagnostic tests should be ordered next?

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Acute dyspnea is the sensation of difficult or uncomfortable breathing that develops over hours to days. Dyspnea is a common symptom with a wide range of causes including respiratory, cardiovascular, metabolic, neuromuscular, and neurologic conditions. Many causes of acute dyspnea are life-threatening, so it is important to have a systematic approach to evaluating these patients.

When approaching a patient with dyspnea, first you should perform an ABCDE assessment, to determine if your patient is unstable or stable. If they are unstable, first check for alarm signs and symptoms! Check for upper airway obstruction by auscultating for stridor, a high-pitched breathing sound, and by directly examining the airway for oropharyngeal swelling or the presence of a foreign body.

If the airway is clear, evaluate the patient’s breathing by assessing respiratory rate and oxygen saturation. A respiratory rate less than 10 or greater than 20 breaths per minute, or oxygen saturation less than 90% requires acute management.

You should also look for red flag features that signal impending respiratory failure such as confusion, inability to speak in complete sentences, and the use of accessory respiratory muscles, such as the scalenes and intercostals.

In this case, stabilize the airway, breathing, and circulation, which may require removing any airway obstruction, endotracheal intubation and mechanical ventilation. Some patients might require supplemental oxygen only, but, in both cases, don’t forget to obtain IV access and put your patient on continuous vital sign monitoring.

Now, here’s a high-yield fact to keep in mind! Causes of acute airway obstruction, that might present with stridor, include anaphylaxis, epiglottitis, and the presence of a foreign body.

Sources

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  2. "Acute dyspnea in the office. 68(9):1803-10. PMID: 14620600." Am Fam Physician. (2003 Nov 1)
  3. "Approach to Adult Patients with Acute Dyspnea" Emergency Medicine Clinics of North America (2016)
  4. "Trowbridge RL. Approach to the patient with dyspnea - case 1. " McGraw Hill (2020.)
  5. "Approach to undifferentiated dyspnea in emergency department: aids in rapid clinical decision-making" International Journal of Emergency Medicine (2018)
  6. "I-AIM (Indication, Acquisition, Interpretation, Medical Decision-making) Framework for Point of Care Lung Ultrasound" Anesthesiology (2017)
  7. "The Differential Diagnosis of Dyspnea" Deutsches Ärzteblatt international (2016)
  8. "An Official American Thoracic Society Statement: Update on the Mechanisms, Assessment, and Management of Dyspnea. " American Thoracic Society Documents, ( Feb 2012)
  9. "Typical and Atypical Symptoms of Acute Coronary Syndrome: Time to Retire the Terms?" Journal of the American Heart Association (2020)
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