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eczema and p. 489
B-complex deficiency p. 63
glucagonomas p. 359
IPEX syndrome p. 100
type IV hypersensitivity reaction p. 111
vitamin B5 deficiency p. 65
vitamin B7 deficiency p. 66
hyper-IgE syndrome p. 114, 716
phenylketonuria p. 82
type I hypersensitivity p. 110
Wiskott-Aldrich syndrome p. 115, 720
atopic dermatitis p. 489
eczema p. 489
eczematous patches p. 674
Atopic dermatitis or atopic eczema is a skin rash that’s particularly common among young children, but can last into adulthood. “Atopic” refers to an allergy, “derm” refers to the skin, and “itis” refers to inflammation.
So atopic dermatitis describes skin inflammation that results from an allergy, more specifically, it happens when the immune system attacks the skin causing a dry, itchy rash on flexor surfaces of the body, areas like the creases of the wrists, the insides of the elbows, and the backs of the knees, as well as exposed skin surfaces like on the face, the hands, and the feet.
The pollen is able to travel through the slightly porous skin, where it gets picked up by an immune cell in the tissue just below.
Those IgE antibodies bind to the surface of other immune cells called mast cells, as well as basophils, which can be found in the tissue layer just below the surface of the skin, and this process called “sensitization”.
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