Autism spectrum disorder


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Autism spectrum disorder

Psychological disorders

Mood disorders

Major depressive disorder


Bipolar disorder

Seasonal affective disorder

Premenstrual dysphoric disorder

Anxiety disorders

Generalized anxiety disorder

Social anxiety disorder

Panic disorder



Obsessive-compulsive disorders

Obsessive-compulsive disorder

Body focused repetitive disorders

Body dysmorphic disorder

Stress-related disorders and abuse

Post-traumatic stress disorder

Physical and sexual abuse

Psychotic disorders

Schizoaffective disorder

Schizophreniform disorder

Delusional disorder


Cognitive and dissociative disorders



Dissociative disorders

Eating disorders

Anorexia nervosa

Bulimia nervosa

Personality disorders

Cluster A personality disorders

Cluster B personality disorders

Cluster C personality disorders

Somatoform and factitious disorders

Somatic symptom disorder

Factitious disorder

Substance use disorders and drugs of abuse

Tobacco dependence

Opioid dependence

Cannabis dependence

Cocaine dependence

Alcohol use disorder

Sleep disorders


Nocturnal enuresis


Night terrors

Narcolepsy (NORD)

Sexual dysfunction disorders

Erectile dysfunction

Male hypoactive sexual desire disorder

Orgasmic dysfunction

Female sexual interest and arousal disorder

Genito-pelvic pain and penetration disorder

Pediatric disorders

Attention deficit hyperactivity disorder

Disruptive, impulse control, and conduct disorders

Learning disability

Fetal alcohol syndrome

Tourette syndrome

Autism spectrum disorder

Rett syndrome

Shaken baby syndrome



Psychiatric emergencies


Serotonin syndrome

Neuroleptic malignant syndrome

Psychological disorders review

Mood disorders: Pathology review

Amnesia, dissociative disorders and delirium: Pathology review

Personality disorders: Pathology review

Eating disorders: Pathology review

Psychological sleep disorders: Pathology review

Psychiatric emergencies: Pathology review

Drug misuse, intoxication and withdrawal: Hallucinogens: Pathology review

Malingering, factitious disorders and somatoform disorders: Pathology review

Anxiety disorders, phobias and stress-related disorders: Pathology Review

Trauma- and stress-related disorders: Pathology review

Schizophrenia spectrum disorders: Pathology review

Drug misuse, intoxication and withdrawal: Stimulants: Pathology review

Drug misuse, intoxication and withdrawal: Alcohol: Pathology review

Developmental and learning disorders: Pathology review

Childhood and early-onset psychological disorders: Pathology review


Autism spectrum disorder


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USMLE® Step 1 questions

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High Yield Notes

6 pages


Autism spectrum disorder

of complete


USMLE® Step 1 style questions USMLE

of complete

A 4-year-old boy is brought to the pediatrician for evaluation of unusual behavior. His parents are concerned about his intellectual development and state that he is “quiet” and almost always by himself, both at home as well as in daycare. He plays with toy trains for hours daily. If the toys are misplaced, he becomes enraged and throws tantrums, which involve him banging his head against the wall. The patient was born full-term, and the pregnancy was uncomplicated. Weight and height are at the 55th percentile. During the examination, the patient does not make eye contact with the physician and sits in the corner playing with his toy trains. The physician attempts to take a train from the patient, which causes him to shout, cry, and flap both hands. The remainder of the physical examination is noncontributory. Which of the following is the most likely diagnosis?

External References

First Aid








Autism spectrum disorder p. 580

double Y males and p. 661

fragile X syndrome p. 60

Intellectual disability

autism and p. 580


Content Reviewers

Rishi Desai, MD, MPH


Tanner Marshall, MS

Vincent Waldman, PhD

Even though everyone develops at slightly different paces, almost everyone hits the same general developmental milestones and learns the same sets of skills on about the same timeline.

These skills progress as the brain develops, and they include: language and communication; social interaction; cognitive skills, like problem solving; and physical milestones, like walking, crawling, and fine motor skills.

If one of these skills doesn’t develop as scheduled, it may, depending on the severity of the delay, be described as a type of neurodevelopmental disorder, neuro referring to the brain.

When certain skills related to socializing and communicating don’t proceed as expected, this can result in isolation.

This is where the name autism originated: auto means “self,” and so autism refers to a condition where somebody might be removed from social interaction and communication, leaving them alone or isolated.

Before 2013, the DSM-4 (which has since been updated to the DSM-5), described autism as one of several pervasive developmental disorders, a category that also includes Asperger’s syndrome, childhood disintegrative disorder, and those pervasive developmental disorders that are not otherwise specified, or PDD-NOS for short.

Asperger’s syndrome was used to describe children who appeared to have characteristics of autism, like difficulties with social interactions or non-verbal communication, but didn’t generally have significant delays in language or cognitive development.

Therefore, Asperger’s syndrome was sometimes referred to as a “high-functioning” form of autism.

Childhood disintegrative disorder was used to describe the late onset of developmental delays.

These children developed typically at first, but then they seemed to lose their acquired social and communication skills sometime between ages two and ten.

“Pervasive developmental disorder: not otherwise” specified is essentially a catch-all category in which patients meet some, but not all, diagnostic criteria of autism, Asperger’s syndrome, or childhood disintegrative disorder.

Researchers found, however, that because these pervasive developmental disorders tend to have similar signs and symptoms, their diagnoses weren’t consistent across different clinics.

As of 2013, the DSM-5, the new and revised edition, removed these terms and replaced them with autism spectrum disorder, or ASD.

The term ASD encompasses all the previous pervasive developmental disorders, but it’s measured on a scale, or a spectrum, that differentiates between patients in two major areas: social communication and interaction deficits, and restrictive or repetitive behavior, interests, and activities.


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