Azoles are synthetic antifungals with broad spectrum activity against various fungal infections. Azoles bind to the ergosterol molecule in the fungal cell membrane and cause holes to form, which damages the cell membrane and eventually kills the fungus. Examples of azoles include drugs like clotrimazole, fluconazole, and itraconazole. Some of the side effects of azoles include nausea and vomiting, gynecomastia, and hepatotoxicity.
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