Beckwith-Wiedemann syndrome
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Beckwith-Wiedemann syndrome p. 366
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Summary
Beckwith-Wiedemann syndrome (BWS) is a genetic imprinting disorder characterized by body overgrowth associated with an increased risk of childhood cancer. The symptoms and severity of BWS can vary greatly from one individual to another. In some cases, the only symptom may be mild overgrowth, while in other cases, there may be multiple major birth defects such as abdominal wall defects. Common symptoms include Hemihypertrophy (one side of the body larger than the other), Macroglossia (enlarged tongue), and Wilms tumor (a type of kidney cancer).
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