Blood brain barrier


Blood brain barrier


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USMLE® Step 1 questions

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High Yield Notes

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Blood brain barrier

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USMLE® Step 1 style questions USMLE

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The blood-brain barrier is absent in several specialized regions collectively called circumventricular organs. Which of the following structures is considered the vomiting center of the brain?  

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Amino acids

blood-brain barrier and p. 511

Basement membrane

blood-brain barrier p. 511

Blood-brain barrier

anesthetics p. 570

astrocytes p. 507

function and mechanism p. 511

l -DOPA p. 569

Cerebrospinal fluid (CSF)

blood-brain barrier and p. 511


blood-brain barrier and p. 511


blood-brain barrier effects p. 511


The blood-brain barrier (BBB) is a semipermeable membrane that regulates what enters and leaves the brain, in order to protect it from harmful substances. The BBB is composed of endothelial cells that line the vasculature of the brain and are connected by tight junctions, which prevent compounds from passing freely between them. The BBB selectively allows molecules such as oxygen and glucose to cross into the brain, while preventing toxins and other foreign substances from entering. Damage or dysfunction of the BBB can allow harmful substances to enter the brain and lead to inflammation and neurological damage.


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