Blood brain barrier

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Blood brain barrier

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Questions

USMLE® Step 1 style questions USMLE

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The blood-brain barrier is absent in several specialized regions collectively called circumventricular organs. Which of the following structures is considered the vomiting center of the brain?  

External References

First Aid

2024

2023

2022

2021

Amino acids

blood-brain barrier and p. 506

Basement membrane

blood-brain barrier p. 506

Blood-brain barrier

anesthetics p. 568

astrocytes p. 502

function and mechanism p. 506

l -DOPA p. 564

Cerebrospinal fluid (CSF)

blood-brain barrier and p. 506

Glucose

blood-brain barrier and p. 506

Infarction

blood-brain barrier effects p. 506

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Summary

The blood-brain barrier (BBB) is a semipermeable membrane that regulates what enters and leaves the brain, in order to protect it from harmful substances. The BBB is composed of endothelial cells that line the vasculature of the brain and are connected by tight junctions, which prevent compounds from passing freely between them. The BBB selectively allows molecules such as oxygen and glucose to cross into the brain, while preventing toxins and other foreign substances from entering. Damage or dysfunction of the BBB can allow harmful substances to enter the brain and lead to inflammation and neurological damage.

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