Brugada syndrome

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Brugada syndrome

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$NOTES NOTES SUDDEN CARDIAC DEATH GENERALLY, WHAT IS IT? PATHOLOGY & CAUSES ▪ Abrupt cessation of cardiac activity (cardiac arrest) in someone asymptomatic up until moment of arrest SIGNS & SYMPTOMS ▪ Asymptomatic DIAGNOSIS TREATMENT MEDICATIONS ▪ According to Advanced Cardiac Life Support protocols OTHER INTERVENTIONS Cardiopulmonary resuscitation (CPR) ▪ Maintains blood ﬂow by mimicking pumping motion heart makes during a medical emergency ▪ Made based on lack of pulse BRUGADA SYNDROME osms.it/brugada-syndrome PATHOLOGY & CAUSES ▪ Condition with characteristic abnormal electrocardiogram ﬁndings → increases risk of sudden cardiac death in healthy individuals ▪ Mixture of normal, abnormal sodium channels within adjacent myocardial tissue can set up heterogenous refractory periods necessary for development of reentrant rhythms → ventricular tachycardia/ ﬁbrillation ▪ 20% associated with SCN5A gene mutation which encodes for sodium ion channel in cell membranes of heart muscle cells RISK FACTORS ▪ Biological males, more common in Asia than North America, Europe COMPLICATIONS ▪ Ventricular ﬁbrillation, high risk of sudden cardiac death CAUSES ▪ Inherited ▫ Autosomal dominant, variable expression OSMOSIS.ORG 127$

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