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Brugada syndrome

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High Yield Notes

6 pages

Flashcards

Brugada syndrome

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Questions

USMLE® Step 1 style questions USMLE

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A 24-year-old male presents to the emergency department after a witnessed syncopal episode. The patient’s parents report they had just finished dinner when their son spontaneously passed out. The patient does not recall the event and had no prodromal features. He is otherwise healthy and does not take any medications, use alcohol, tobacco, or illicit substances. Vital signs are within normal limits, and physical examination is unremarkable. Electrocardiogram is demonstrated below:


Image reproduced from Wikimedia Commons  

If left untreated this patient is at risk for which of the following complications?  

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Brugada syndrome p. 299

Brugada syndrome p. 312, 308

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Summary

Brugada syndrome is a potentially life-threatening condition that can cause sudden cardiac death. The condition is characterized by abnormal heart rhythms (arrhythmias) on ECG and a predisposition to developing ventricular fibrillation, a particularly dangerous type of arrhythmia. People with Brugada syndrome often have no symptoms, making the condition difficult to diagnose. However, in some cases, people with the condition may experience episodes of palpitations, fatigue, and shortness of breath.

Sources

  1. "Robbins Basic Pathology" Elsevier (2017)
  2. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  3. "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
  4. "Brugada syndrome: Diagnosis, risk stratification and management" Archives of Cardiovascular Diseases (2017)
  5. "Brugada Syndrome" Methodist DeBakey Cardiovascular Journal (2014)

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