Cavernous sinus thrombosis




Cavernous sinus thrombosis

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Nervous system pathology review

Congenital neurological disorders: Pathology review

Headaches: Pathology review

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Cerebral vascular disease: Pathology review

Traumatic brain injury: Pathology review

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Movement disorders: Pathology review

Neuromuscular junction disorders: Pathology review

Demyelinating disorders: Pathology review

Adult brain tumors: Pathology review

Pediatric brain tumors: Pathology review

Neurocutaneous disorders: Pathology review


Cavernous sinus thrombosis


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USMLE® Step 2 questions

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High Yield Notes

13 pages


Cavernous sinus thrombosis

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USMLE® Step 2 style questions USMLE

of complete

A 41-year-old man comes to the office because of a 1-day history of fever, headache, and bilateral periorbital and mid-facial swelling. The day prior to the onset of the symptoms, the patient had attempted to burst a furuncle in the inner margin of his right nostril. His past medical history is noncontributory, and he does not take any medications. He had last traveled to India 4 months ago. Temperature is 38.1°C (100.5°F), pulse is 66/min, respirations are 12/min, and blood pressure is 124/72 mmHg. Physical examination shows marked facial and periorbital swelling with bilateral blepharoptosis, chemosis, and proptosis. On fundoscopy, there is no evidence of optic disc swelling. The patient has a full range of eye movements but complains of pain with eye movement. A high-resolution orbital CT with contrast demonstrates bilateral septic cavernous sinus thrombosis. Occlusion of which of the following veins is the most likely underlying cause of this patient’s condition? 

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A cavernous sinus thrombosis is a rare, life-threatening condition that occurs when a blood clot blocks the cavernous sinus, which is one of the veins that drain blood from your head and brain. It is usually caused by a bacterial infection that has spread from the sinuses, ear, or nose. Symptoms may include headache, eye pain and swelling, red eye, fever, nausea, vomiting, and loss of balance. A cavernous sinus thrombosis can lead to permanent vision loss, coma, or death if left untreated.


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