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Cell-mediated immunity of CD4 cells
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cell surface proteins p. 108
cytokine secretion p. 106
in granulomatous diseases p. NaN
helper p. 98
And there are two types of T cells.
Helper T cells primarily support other immune cells, whereas cytotoxic T cells kill cells that are infected with a pathogen or are cancerous.
That makes sense since CD4 helper T cells interact with other immune cells to stimulate them.
Now, when a T cell is initially formed it’s considered naive.
This naive T cell is a bit like a student in school that isn’t ready to choose a career path.
This process of priming requires two signals.
This antigen has to bind perfectly to the T cell receptor.
This region, which includes the T cell receptor which binds to the MHC-Antigen, and CD4 and CD28 which bind with B7, is called the immune synapse.
CD4 cells are white blood cells that play a vital role in the body's cell-mediated immunity. Cell-mediated immunity is the part of the immune system which relies on phagocytes, cytotoxic T-lymphocytes, and the release of various cytokines to fight off an infection. CD4 cells recognize and destroy infected cells by binding to special proteins on the surface of the infected cells called antigens. Once attached, the CD4 cells release molecules called cytokines which activate other immune cells to destroy the infected cell.
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