Cerebral circulation

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Cerebral circulation

CVD

CVD

Introduction to the cardiovascular system
Anatomy of the heart
Anatomy of the coronary circulation
Anatomy clinical correlates: Heart
Anatomy of the superior mediastinum
Anatomy of the inferior mediastinum
Anatomy clinical correlates: Mediastinum
Development of the cardiovascular system
Fetal circulation
Cardiac muscle histology
Artery and vein histology
Arteriole, venule and capillary histology
Cardiovascular system anatomy and physiology
Lymphatic system anatomy and physiology
Coronary circulation
Blood pressure, blood flow, and resistance
Pressures in the cardiovascular system
Laminar flow and Reynolds number
Resistance to blood flow
Compliance of blood vessels
Control of blood flow circulation
Microcirculation and Starling forces
Measuring cardiac output (Fick principle)
Stroke volume, ejection fraction, and cardiac output
Cardiac contractility
Frank-Starling relationship
Cardiac preload
Cardiac afterload
Law of Laplace
Cardiac and vascular function curves
Altering cardiac and vascular function curves
Cardiac cycle
Cardiac work
Pressure-volume loops
Changes in pressure-volume loops
Physiological changes during exercise
Cardiovascular changes during hemorrhage
Cardiovascular changes during postural change
Normal heart sounds
Abnormal heart sounds
Action potentials in myocytes
Action potentials in pacemaker cells
Excitability and refractory periods
Cardiac excitation-contraction coupling
Electrical conduction in the heart
Cardiac conduction velocity
ECG basics
ECG rate and rhythm
ECG intervals
ECG QRS transition
ECG axis
ECG normal sinus rhythm
ECG cardiac infarction and ischemia
ECG cardiac hypertrophy and enlargement
Baroreceptors
Chemoreceptors
Renin-angiotensin-aldosterone system
Arterial disease
Angina pectoris
Stable angina
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Myocardial infarction
Prinzmetal angina
Coronary steal syndrome
Peripheral artery disease
Subclavian steal syndrome
Aneurysms
Aortic dissection
Vasculitis
Behcet's disease
Kawasaki disease
Hypertension
Hypertensive emergency
Renal artery stenosis
Coarctation of the aorta
Cushing syndrome
Conn syndrome
Pheochromocytoma
Polycystic kidney disease
Hypotension
Orthostatic hypotension
Abetalipoproteinemia
Familial hypercholesterolemia
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Hyperlipidemia
Chronic venous insufficiency
Thrombophlebitis
Deep vein thrombosis
Lymphedema
Lymphangioma
Shock
Vascular tumors
Human herpesvirus 8 (Kaposi sarcoma)
Angiosarcomas
Truncus arteriosus
Transposition of the great vessels
Total anomalous pulmonary venous return
Tetralogy of Fallot
Hypoplastic left heart syndrome
Patent ductus arteriosus
Ventricular septal defect
Atrial septal defect
Atrial flutter
Atrial fibrillation
Premature atrial contraction
Atrioventricular nodal reentrant tachycardia (AVNRT)
Wolff-Parkinson-White syndrome
Ventricular tachycardia
Brugada syndrome
Premature ventricular contraction
Long QT syndrome and Torsade de pointes
Ventricular fibrillation
Atrioventricular block
Bundle branch block
Pulseless electrical activity
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Pulmonary valve disease
Mitral valve disease
Aortic valve disease
Dilated cardiomyopathy
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Hypertrophic cardiomyopathy
Heart failure
Cor pulmonale
Endocarditis
Myocarditis
Rheumatic heart disease
Pericarditis and pericardial effusion
Cardiac tamponade
Dressler syndrome
Cardiac tumors
Acyanotic congenital heart defects: Pathology review
Cyanotic congenital heart defects: Pathology review
Atherosclerosis and arteriosclerosis: Pathology review
Coronary artery disease: Pathology review
Peripheral artery disease: Pathology review
Valvular heart disease: Pathology review
Cardiomyopathies: Pathology review
Heart failure: Pathology review
Supraventricular arrhythmias: Pathology review
Ventricular arrhythmias: Pathology review
Heart blocks: Pathology review
Aortic dissections and aneurysms: Pathology review
Pericardial disease: Pathology review
Endocarditis: Pathology review
Hypertension: Pathology review
Shock: Pathology review
Vasculitis: Pathology review
Cardiac and vascular tumors: Pathology review
Dyslipidemias: Pathology review
Sympatholytics: Alpha-2 agonists
Adrenergic antagonists: Presynaptic
Adrenergic antagonists: Alpha blockers
Adrenergic antagonists: Beta blockers
ACE inhibitors, ARBs and direct renin inhibitors
Thiazide and thiazide-like diuretics
Calcium channel blockers
cGMP mediated smooth muscle vasodilators
Class I antiarrhythmics: Sodium channel blockers
Class II antiarrhythmics: Beta blockers
Class III antiarrhythmics: Potassium channel blockers
Class IV antiarrhythmics: Calcium channel blockers and others
Lipid-lowering medications: Statins
Lipid-lowering medications: Fibrates
Miscellaneous lipid-lowering medications
Positive inotropic medications
Cardiomyopathies: Clinical
Congenital heart defects: Clinical
Valvular heart disease: Clinical
Infective endocarditis: Clinical
Pericardial disease: Clinical
Chest trauma: Clinical
Hypertension: Clinical
Pulmonary hypertension
Aortic aneurysms and dissections: Clinical
Raynaud phenomenon
Peripheral vascular disease: Clinical
Heart failure: Clinical
Coronary artery disease: Clinical
Deep vein thrombosis and pulmonary embolism: Pathology review
Fascia, vessels and nerves of the upper limb
Vessels and nerves of the forearm
Vessels and nerves of the hand
Anatomy of the abdominal viscera: Blood supply of the foregut, midgut and hindgut
Fascia, vessels, and nerves of the lower limb
Vessels and nerves of the gluteal region and posterior thigh
Anatomy of the popliteal fossa
Ventilation
Ventilation-perfusion ratios and V/Q mismatch
Gas exchange in the lungs, blood and tissues
Oxygen binding capacity and oxygen content
Oxygen-hemoglobin dissociation curve
Carbon dioxide transport in blood
Trypanosoma cruzi (Chagas disease)
Yellow fever virus
Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species
Arteriovenous malformation
Cerebral circulation

Assessments

Flashcards

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USMLE® Step 1 questions

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High Yield Notes

5 pages

Flashcards

Cerebral circulation

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Questions

USMLE® Step 1 style questions USMLE

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Therapeutic hyperventilation may treat acute cerebral edema unresponsive to other interventions. Which changes during hyperventilation enhance cerebral perfusion pressure (CPP)?  

External References

First Aid

2024

2023

2022

2021

Cerebral perfusion p. 512

Cerebral perfusion pressure (CPP) p. 513

Transcript

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With cerebral circulation, cerebral stands for "brain," and circulation, refers to “blood flow.”

So, cerebral circulation is the movement of blood through the vessels that supply the brain and surrounding structures.

Our brain is responsible for complex functions such as thinking, feeling, memory, movement, vision, and speech.

Therefore, some of the devastating effects of oxygen deprivation to the brain include strokes, seizures, coma, and even death.

As a result, the brain requires a very efficient cerebral circulation to provide oxygen and nutrients, and remove carbon dioxide and wastes.

Now, like any other organ in the body, the blood supply to the brain, originates from the aorta.

Arising from the heart’s left ventricle, it goes on to form the aortic arch. Here, the brachiocephalic artery, originates first.

This branch gives off the right subclavian artery and the right common carotid artery.

Then a bit further along the aortic arch, the left common carotid artery arises, followed by the left subclavian artery.

The subclavian arteries give off right and left vertebral arteries, which ascend through the intervertebral feramina up to the brain.

Because the consequences of hypoxia to the brain are so devastating, the brain is safeguarded by having a dual circulation, an anterior circulation, originating from the carotids, and a posterior circulation, originating from the vertebral arteries.

The two circulations eventually meet up, creating what’s known as the circle of Willis.

Alright, the anterior circulation starts in the neck, where the common carotid splits into the external and internal branches, the internal carotid arteries, passes through the carotid canal of the temporal bone of the skull and into the cranial cavity to supply the brain.

Once, it enters the cranial cavity, the internal carotid artery gives off branches. First are the middle cerebral arteries that supply blood to the temporal and parietal lobes.

Second are the anterior cerebral arteries, which provide to the midline portions of the frontal lobes and superior medial parietal lobes of the brain.

Both anterior cerebral arteries are connected through the anterior communicating artery, forming the anterior portion of the circle of willis.

The posterior circulation starts with the vertebral arteries,which head up towards the cranium through the transverse foramina of the cervical vertebrae and then through the foramen magnum into the cranial cavity.

Summary

The cerebral circulation is responsible for delivering oxygen and nutrients to the brain and removing carbon dioxide and other waste products. To ensure an uninterrupted blood supply to the brain, cerebral circulation consists of anterior and posterior parts. These two circulations, together, form a network of vessels known as the arterial circle of Willis. The anterior circulation consists of the internal carotid arteries and branches, which are the middle and anterior cerebral arteries. The anterior communicating artery connects the two anterior cerebral arteries.

The posterior circulation comes from the two vertebral arteries, which merge into the basilar artery and split into posterior cerebral arteries. Posterior cerebral arteries give off the left and right posterior communicating arteries, which then merge with the internal carotid arteries. Venous blood drains into the dural sinuses, which empty into the jugular veins and return to the heart through the superior vena cava.