00:00 / 00:00
Bacterial structure and functions
Bacillus anthracis (Anthrax)
Bacillus cereus (Food poisoning)
Corynebacterium diphtheriae (Diphtheria)
Clostridium botulinum (Botulism)
Clostridium difficile (Pseudomembranous colitis)
Clostridium tetani (Tetanus)
Streptococcus agalactiae (Group B Strep)
Streptococcus pyogenes (Group A Strep)
Bartonella henselae (Cat-scratch disease and Bacillary angiomatosis)
Legionella pneumophila (Legionnaires disease and Pontiac fever)
Salmonella typhi (typhoid fever)
Yersinia pestis (Plague)
Vibrio cholerae (Cholera)
Bordetella pertussis (Whooping cough)
Francisella tularensis (Tularemia)
Haemophilus ducreyi (Chancroid)
Mycobacterium tuberculosis (Tuberculosis)
Mycobacterium avium complex (NORD)
Gardnerella vaginalis (Bacterial vaginosis)
Coxiella burnetii (Q fever)
Ehrlichia and Anaplasma
Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species
Borrelia burgdorferi (Lyme disease)
Borrelia species (Relapsing fever)
Treponema pallidum (Syphilis)
0 / 32 complete
0 / 9 complete
Chlamydia trachomatis p. , 147
Chlamydia trachomatis p. , 731
eosinophilia p. 147
pelvic inflammatory disease p. 147
pneumonia p. 176
serotypes p. 147
treatment p. 731
UTIs p. 621
Chlamydia trachomatis in p. 147
Chlamydia trachomatis or just C. trachomatis, is a gram-negative bacteria that strictly infects humans, and it’s divided into 15 serotypes, also known as serovars.
A serovar groups together bacteria with similar surface antigens, and so are likely to cause the same type of infection.
Serotypes A through C cause chlamydia conjunctivitis in adults, which also called trachoma.
Serotypes D through K cause a genital infection called chlamydia.
Lastly, serotypes L1, L2 and L3 - and there’s no particular reason that these are numbered - infect the lymph nodes, causing a disease called lymphogranuloma venereum, or LVG.
No matter the serotype, C. trachomatis is a gram-negative bacteria, meaning it cannot retain the crystal violet stain used during gram staining.
However, unlike other common gram-negative bacteria which have a thin layer of murein, also known as peptidoglycan in their cell wall, the cell wall of C. trachomatis has no any murein at all - so it can’t retain pink safranin dye used during Gram staining, either.
So, C. trachomatis is best stained with Giemsa stain, which colors them pinkish-blue.
What is more, unlike most bacteria, chlamydia requires vial cells or embryonated hen's egg for culture, which is technically difficult and expensive, so cultures are only done for research purposes.
Chlamydia trachomatis is also non-motile, and an obligate aerobe, meaning it absolutely depends on oxygen to survive.
It’s also an obligate intracellular pathogen, because it’s unable to make its own ATP for energy, so it needs to use another cell’s resources.
Ok now, when C. trachomatis enters a host cell, it undergoes a life cycle that alternates between two distinct forms.
The first is the small spore-looking form called the elementary body, and it’s the infective form of this bacteria.
After the elementary body enters the host cell, it gets enclosed in a vacuole called an inclusion, where it transforms into a metabolically active, star-looking form, called the reticulate body.
Chlamydia trachomatis is a gram-negative, non-motile bacterium and an intracellular pathogen known to cause sexually transmitted chlamydia infection and associated complications, including infertility and pelvic inflammatory disease (PID). It is passed from one person to another through unprotected sexual intercourse, but it can also be spread from a mother to her baby during childbirth.
Latest on COVID-19
Nurse Practitioner (NP)
Physician Assistant (PA)
Create custom content
Raise the Line Podcast
Copyright © 2024 Elsevier, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
Cookies are used by this site.
Terms and Conditions
USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.