Chorioamnionitis

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Summary of Chorioamnionitis

Intra-amniotic infection (formerly called chorioamnionitis) is infection of the chorion, amnion, amniotic fluid, placenta, or a combination. Infection increases risk of obstetric complications and problems in the fetus and neonate. Symptoms include fever, uterine tenderness, foul-smelling vaginal discharge, and maternal and fetal tachycardia. Diagnosis is by specific clinical criteria or, for subclinical infection, analysis of amniotic fluid. Treatment includes broad-spectrum antibiotics and delivery.

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Chorioamnionitis

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Chorioamnionitis

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A 26-year-old woman, gravida 2, para 1, at 40 weeks’ gestation comes to the gynecologic emergency department due to a history of amniotic fluid loss for the past 10 hours with uterine tenderness. She has no significant past medical history. Temperature is 39°C (102.2°F), pulse is 96/min, respirations are 20/min, and blood pressure is 100/60 mm Hg. Uterine contractions are sporadic and baseline fetal heart rate is 162/min. Speculum examination shows purulent amniotic fluid exuding from the cervical os. Which of the following clinical findings best describes the most likely diagnosis?

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