Congenital toxoplasmosis

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Flashcards

Congenital toxoplasmosis

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Questions

USMLE® Step 1 style questions USMLE

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A 35-year-old primigravid woman has a stillbirth at 21-weeks of gestation. The patient has been consistent with her prenatal care and taking daily prenatal vitamins. She returned from a trip to Nigeria 6 months ago. Past medical history is notable for type I diabetes mellitus. She developed a fever, swollen lymph nodes, and muscle aches during the pregnancy that lasted for a week. A fetal autopsy is notable for scattered intracranial calcifications, hydrocephalus, macrocephaly, and hepatosplenomegaly. Which of the following maternal exposures most likely resulted in this fetus’s condition?

External References

First Aid

2024

2023

2022

2021

Chorioretinitis

congenital toxoplasmosis p. 181

Oocysts

Toxoplasmosis p. 153

Toxoplasmosis

PCL vs p. 435

prophylaxis p. 191, 194

pyrimethamine p. 198

Summary

Congenital toxoplasmosis is a parasitic disease that affects fetuses and newborns. It is caused by the parasite Toxoplasma gondii. It is transmitted from the mother to the fetus during pregnancy and can cause serious problems to the unborn child. Newborns with congenital toxoplasmosis usually present with low birth weight, blindness, hepatosplenomegaly, hydrocephalus, and diffuse intracranial calcifications.

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