Conn syndrome
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Conn syndrome
Endocrine system
Adrenal disorders
Congenital disorders
Diabetes mellitus and other disorders of the endocrine pancreas
Multiple endocrine neoplasia (MEN1, MEN2)
Parathyroid disorders
Pituitary disorders
Thyroid gland disorders
Endocrine system pathology review
Adrenal masses: Pathology review
Cushing syndrome and Cushing disease: Pathology review
Disorders of sex chromosomes: Pathology review
Disorders of sexual development and sex hormones: Pathology review
Diabetes mellitus: Pathology review
Neuroendocrine tumors of the gastrointestinal system: Pathology review
Multiple endocrine neoplasia: Pathology review
Parathyroid disorders and calcium imbalance: Pathology review
Diabetes insipidus and SIADH: Pathology review
Hypopituitarism: Pathology review
Pituitary tumors: Pathology review
Hyperthyroidism: Pathology review
Hypothyroidism: Pathology review
Thyroid nodules and thyroid cancer: Pathology review
Assessments
Flashcards
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USMLE® Step 1 questions
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High Yield Notes
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Flashcards
Conn syndrome
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Questions
USMLE® Step 1 style questions USMLE
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A 44-year-old man comes to his physician complaining of muscle weakness and headaches for the past 2 months. He is a construction worker and has found it difficult to lift large objects during the job. The patient has no significant past medical history, but he states his blood pressure was “high” at a recent health fair. Temperature is 37.0°C (98.6°F), pulse is 82/min, and blood pressure is 165/92 mm Hg. Physical examination reveals no abnormalities. Laboratory testing reveals the following findings:
Serum renin levels are decreased. Which of the following is the most likely cause of this patient’s condition?
| Laboratory Value | Result |
| Serum | |
| Sodium | 147 mEq/L |
| Potassium | 2.9 mEq/L |
| Chloride | 105 mEq/L |
| HCO3- | 32 mEq/L |
| Creatinine | 0.6 mg/dL |
| Glucose | 94 mg/dL |
Serum renin levels are decreased. Which of the following is the most likely cause of this patient’s condition?
Summary
Conn syndrome, also known as primary hyperaldosteronism, is a rare disorder caused by high levels of aldosterone hormone. Aldosterone is produced by the adrenal gland, promotes Sodium conservation in the kidney, and helps the body keep Sodium and water balance.
In Conn syndrome, the adrenal gland produces too much aldosterone, and this causes the body to retain too much salt and water. This can lead to high blood pressure, edema, and hypokalemia (low potassium levels in the blood). Conn syndrome can be caused by adrenal hyperplasia or adrenal adenoma.