Coronary steal syndrome

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Coronary steal syndrome

Cardiovascular system

Vascular disorders

Arterial disease

Angina pectoris

Stable angina

Unstable angina

Myocardial infarction

Prinzmetal angina

Coronary steal syndrome

Peripheral artery disease

Subclavian steal syndrome

Aneurysms

Aortic dissection

Vasculitis

Behcet's disease

Kawasaki disease

Hypertension

Hypertensive emergency

Renal artery stenosis

Coarctation of the aorta

Cushing syndrome

Conn syndrome

Pheochromocytoma

Polycystic kidney disease

Hypotension

Orthostatic hypotension

Abetalipoproteinemia

Familial hypercholesterolemia

Hypertriglyceridemia

Hyperlipidemia

Chronic venous insufficiency

Thrombophlebitis

Deep vein thrombosis

Lymphedema

Lymphangioma

Shock

Vascular tumors

Human herpesvirus 8 (Kaposi sarcoma)

Angiosarcomas

Congenital heart defects

Truncus arteriosus

Transposition of the great vessels

Total anomalous pulmonary venous return

Tetralogy of Fallot

Hypoplastic left heart syndrome

Patent ductus arteriosus

Ventricular septal defect

Coarctation of the aorta

Atrial septal defect

Cardiac arrhythmias

Atrial flutter

Atrial fibrillation

Premature atrial contraction

Atrioventricular nodal reentrant tachycardia (AVNRT)

Wolff-Parkinson-White syndrome

Ventricular tachycardia

Brugada syndrome

Premature ventricular contraction

Long QT syndrome and Torsade de pointes

Ventricular fibrillation

Atrioventricular block

Bundle branch block

Pulseless electrical activity

Valvular disorders

Tricuspid valve disease

Pulmonary valve disease

Mitral valve disease

Aortic valve disease

Cardiomyopathies

Dilated cardiomyopathy

Restrictive cardiomyopathy

Hypertrophic cardiomyopathy

Heart failure

Heart failure

Cor pulmonale

Cardiac infections

Endocarditis

Myocarditis

Rheumatic heart disease

Pericardial disorders

Pericarditis and pericardial effusion

Cardiac tamponade

Dressler syndrome

Cardiac tumors

Cardiac tumors

Cardiovascular system pathology review

Acyanotic congenital heart defects: Pathology review

Cyanotic congenital heart defects: Pathology review

Atherosclerosis and arteriosclerosis: Pathology review

Coronary artery disease: Pathology review

Peripheral artery disease: Pathology review

Valvular heart disease: Pathology review

Cardiomyopathies: Pathology review

Heart failure: Pathology review

Supraventricular arrhythmias: Pathology review

Ventricular arrhythmias: Pathology review

Heart blocks: Pathology review

Aortic dissections and aneurysms: Pathology review

Pericardial disease: Pathology review

Endocarditis: Pathology review

Hypertension: Pathology review

Shock: Pathology review

Vasculitis: Pathology review

Cardiac and vascular tumors: Pathology review

Dyslipidemias: Pathology review

Assessments

Coronary steal syndrome

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USMLE® Step 1 questions

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Coronary steal syndrome

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Questions

USMLE® Step 1 style questions USMLE

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A 60-year-old man is brought to the emergency department due to chest pain that started suddenly 15 minutes ago while playing with his grandchildren. The patient describes the pain as “pressure and tightness” located in the center of his chest. The patient reports that he occasionally experiences mild chest discomfort when going up the stairs. Medical history is significant for a 30-pack-year smoking history, hypercholesterolemia, and hypertension. The patient is given a sublingual medication while in the emergency department, and the symptoms resolve within a few minutes. Which of the following sets of hemodynamic changes is most likely to be seen in this patient following the administration of this medication?  

*(-) decrease, (0) no effect, (+) increase  

External References

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Transcript

Content Reviewers

Viviana Popa, MD

Contributors

Robyn Hughes, MScBMC

Jahnavi Narayanan, MBBS

Alex Aranda

Salma Ladhani, MD

Coronary steal syndrome is a condition that occurs due to dilation of coronary arteries in the presence of coronary artery disease, which is when there’s a partial or complete blockage in the lumen of another coronary artery.

The result is a redirection of blood flow from heart muscle supplied by the blocked artery, to other regions of the heart.

Coronary steal syndrome is a finding observed during a pharmacological cardiac stress test, which is used to diagnose coronary artery disease.

Now, the heart pumps out blood for all of our organs and tissues to use - but the heart also needs blood.

So it also pumps blood to itself, through the coronary arteries on the outside of the heart.

And coronary arteries are linked to one another through teeny tiny blood vessels called collateral vessels, which are normally in an inactive state, meaning blood doesn’t flow through them.

Now, with coronary artery disease, there’s ischemia, or reduced blood flow to the region of myocardium supplied by that artery.

In this context, collateral circulation may become active. For example, let’s say two coronary arteries,

A and B, are linked by a collateral vessel, and coronary artery B has developed a block.

As a result of ischemia, in the myocardium supplied by coronary artery B, the myocardial cells don’t receive enough oxygen, which is called hypoxia.

In response to hypoxia, myocardial cells release signalling molecules called cytokines, which cause dilation of the segment of coronary artery B beyond the blockage.

Sources

  1. "Robbins Basic Pathology" Elsevier (2017)
  2. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  3. "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
  4. "Coronary Steal" Chest (1989)
  5. "Coronary steal induced by angiogenesis following bypass surgery" Heart (2005)
Elsevier

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