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Crigler-Najjar syndrome

Summary of Crigler-Najjar syndrome
Crigler–Najjar syndrome is a rare inherited disorder affecting the metabolism of bilirubin. It is caused by an absent UDP-glucuronosyltransferase enzyme. The disorder results in a form of nonhemolytic jaundice, which results in high levels of unconjugated bilirubin and often leads to brain damage in infants. The disorder is autosomal recessive.

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Pathology

Gastrointestinal system

Peritoneum and peritoneal cavity disorders
Upper gastrointestinal tract disorders
Lower gastrointestinal tract disorders
Liver, gallbladder and pancreas disorders