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Cryptococcus neoformans

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Cryptococcus neoformans

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High Yield Notes
12 pages
Flashcards

Cryptococcus neoformans

12 flashcards
Questions

USMLE® Step 1 style questions USMLE

1 questions
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A 45-year-old man is brought to the emergency department due to confusion and altered mental status. His friend, who brought him in, states the patient has been complaining of fevers accompanied by malaise for the past 2 weeks. The patient is currently living in a homeless shelter, but oftentimes he is seen sleeping on the streets by his friends. Medical history is unknown, but a month ago the patient was hospitalized for Pneumocystis jirovecii (formerly P. carinii) pneumonia. Temperature is 38.5°C (101.3°F), pulse is 80/min, and blood pressure is 135/85 mmHg. On physical examination, the patient is lethargic and mildly confused. Neck is supple, and there are no focal signs. The patient’s arms show multiple needle marks. The pathogen most likely responsible for this patient’s condition is most likely to show which of the following on further testing?  

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Summary

Cryptococcus neoformans is an encapsulated yeast known to cause cryptococcal meningitis. This form of meningitis is mostly seen in immunocompromised individuals such as those with HIV/AIDS, or those who have had a recent organ transplant. Cryptococcus neoformans is naturally found in soil and pigeon feces. Symptoms include headache and neck pain, nausea, photophobia, vomiting, and fever.