Cyanotic congenital heart defects: Pathology review

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Questions

USMLE® Step 1 style questions USMLE

of complete

A 1-day-old female newborn is being evaluated in the neonatal intensive care unit for severe respiratory distress and cyanosis. The patient was born at 38 weeks gestation via vaginal delivery to a 30-year-old woman who had minimal prenatal care. Temperature is 36.4°C (97.5°F), pulse is 150/min, blood pressure is 87/55 mm Hg, and respiration rate is 60/min. An electrocardiogram reveals left axis deviation with a superior axis and chest x-ray shows decreased pulmonary markings and a hypoplastic right ventricle. Which of the following is the most likely diagnosis?  

Sources

  1. "Pathophysiology of Heart Disease" Wolters Kluwer Health (2015)
  2. "Robbins Basic Pathology" Elsevier (2017)
  3. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  4. "Cyanosis of the newborn infant" The Journal of Pediatrics (1970)
  5. "Diagnosis and management of the newborn with suspected congenital heart disease" Clin Perinatol (2001)
Elsevier

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