Cystic fibrosis is an autosomal recessive disorder that is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator protein. This protein is involved in production of sweat, digestive fluids, and mucus. When it is mutated, secretions which are usually thin instead become thick. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in males among others.
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