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Cytomegalovirus

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Cytomegalovirus

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High Yield Notes
10 pages
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Cytomegalovirus

25 flashcards
Questions

USMLE® Step 1 style questions USMLE

2 questions
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A 17-year-old girl presents for evaluation of sore throat and fatigue. The patient's symptoms have been ongoing for the past week. According to the patient, “I think I picked up a bug from my partner, he had a similar illness about three-weeks ago.” The patient is otherwise healthy and does not take any medications. Temperature is 38.2°C (100.8°F), pulse is 80/min, respirations are 14/min, and blood pressure is 125/71 mmHg. Physical examination demonstrates posterior auricular and posterior cervical lymphadenopathy, as well as bilateral tonsillar swelling. A heterophile antibody screen is negative. Which of the following is the most likely pathogen responsible for this patient’s symptoms?

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Summary

Cytomegalovirus (CMV), also known as human herpes 5, is a double-stranded DNA virus. It is usually asymptomatic in immunocompetent individuals, but can present with severe diseases in immunocompromised individuals such as those with HIV/AIDS. It can cause retinitis, esophagitis, and retinitis pneumonia. On microscopic examination, infected cells can present with characteristic "owl eye" inclusion bodies. CMV is spread through body fluids such as saliva, urine, and sexual contact but can also be spread via transplanted organs.